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Ligand

NameCHEMBL3908870
Molecular formulaC19H26N2O2
IUPAC name1-[4-(1,3-dihydroisoindol-2-yl)butyl]-4,4-dimethylpiperidine-2,6-dione
Molecular weight314.429
Hydrogen bond acceptor3
Hydrogen bond donor0
XlogP2.2
SynonymsSCHEMBL20358602
BDBM50199137
Inchi KeyHWHPJDOZGZLVJB-UHFFFAOYSA-N
Inchi IDInChI=1S/C19H26N2O2/c1-19(2)11-17(22)21(18(23)12-19)10-6-5-9-20-13-15-7-3-4-8-16(15)14-20/h3-4,7-8H,5-6,9-14H2,1-2H3
PubChem CID134133064
ChEMBLCHEMBL3908870
IUPHARN/A
BindingDB50199137
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

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Total entries: 9
Page:  / 1 

GLASS IDNameUniProtGeneSpeciesLength
5494655-hydroxytryptamine receptor 1AP08908HTR1AHomo sapiens (Human)422
5494735-hydroxytryptamine receptor 2AP28223HTR2AHomo sapiens (Human)471
5494705-hydroxytryptamine receptor 2BP41595HTR2BHomo sapiens (Human)481
5494715-hydroxytryptamine receptor 2CP28335HTR2CHomo sapiens (Human)458
5494685-hydroxytryptamine receptor 7P34969HTR7Homo sapiens (Human)479
549469D(2) dopamine receptorP14416DRD2Homo sapiens (Human)443
549466D(3) dopamine receptorP35462DRD3Homo sapiens (Human)400
549472D(4) dopamine receptorP30729Drd4Rattus norvegicus (Rat)387
549467Histamine H1 receptorP35367HRH1Homo sapiens (Human)487

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