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Ligand

NameMLS003171619
Molecular formulaC21H16ClN3O3
IUPAC nameN-[3-chloro-4-[(1S,2R,6S,7R)-3,5-dioxo-4-azatricyclo[5.2.1.02,6]dec-8-en-4-yl]phenyl]pyridine-2-carboxamide
Molecular weight393.827
Hydrogen bond acceptor4
Hydrogen bond donor1
XlogP2.6
SynonymsCHEBI:92530
NCGC00386910-01
SMR001875504
Inchi KeyLJUABYFUJVRUSJ-FRVJLOGJSA-N
Inchi IDInChI=1S/C21H16ClN3O3/c22-14-10-13(24-19(26)15-3-1-2-8-23-15)6-7-16(14)25-20(27)17-11-4-5-12(9-11)18(17)21(25)28/h1-8,10-12,17-18H,9H2,(H,24,26)/t11-,12+,17-,18+
PubChem CID54752951
ChEMBLCHEMBL1921961
IUPHARN/A
BindingDBN/A
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

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Total entries: 6
Page:  / 1 

GLASS IDNameUniProtGeneSpeciesLength
189224Metabotropic glutamate receptor 4P31423Grm4Rattus norvegicus (Rat)912
189226Metabotropic glutamate receptor 4Q14833GRM4Homo sapiens (Human)912
189222Metabotropic glutamate receptor 5P31424Grm5Rattus norvegicus (Rat)1203
189221Metabotropic glutamate receptor 6O15303GRM6Homo sapiens (Human)877
189223Metabotropic glutamate receptor 6P35349Grm6Rattus norvegicus (Rat)871
189225Metabotropic glutamate receptor 7P35400Grm7Rattus norvegicus (Rat)915

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