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Ligand

Name475150-69-7
Molecular formulaC27H35N3O2
IUPAC name(2R)-1-benzyl-N-(3-spiro[1H-2-benzofuran-3,4'-piperidine]-1'-ylpropyl)pyrrolidine-2-carboxamide
Molecular weight433.596
Hydrogen bond acceptor4
Hydrogen bond donor1
XlogP3.3
SynonymsBanyu Compound-24
(R)-N-(3-(3H-spiro[isobenzofuran-1,4'-piperidine]-1'-yl)propyl)-1-benzylpyrrolidine-2-carboxamide
CHEMBL201945
C-24
BAN ORL 24 HCL
[ Show all ]
Inchi KeyMAKMQGKJURAJEN-RUZDIDTESA-N
Inchi IDInChI=1S/C27H35N3O2/c31-26(25-12-6-17-30(25)20-22-8-2-1-3-9-22)28-15-7-16-29-18-13-27(14-19-29)24-11-5-4-10-23(24)21-32-27/h1-5,8-11,25H,6-7,12-21H2,(H,28,31)/t25-/m1/s1
PubChem CID10296561
ChEMBLCHEMBL201945
IUPHAR7361
BindingDB50181392
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

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Total entries: 5
Page:  / 1 

GLASS IDNameUniProtGeneSpeciesLength
200762Delta-type opioid receptorP41143OPRD1Homo sapiens (Human)372
200763Kappa-type opioid receptorP41145OPRK1Homo sapiens (Human)380
200765Mu-type opioid receptorP35372OPRM1Homo sapiens (Human)400
200761Nociceptin receptorP41146OPRL1Homo sapiens (Human)370
200764Nociceptin receptorP35377Oprl1Mus musculus (Mouse)367

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