Home Research Services Publications People Teaching Job Opening Facilities News Forum Lab Only
Online Services

I-TASSER QUARK LOMETS COACH COFACTOR MetaGO MUSTER SEGMER FG-MD ModRefiner REMO DEMO SPRING COTH BSpred SVMSEQ ANGLOR BSP-SLIM SAXSTER ThreaDom ThreaDomEx EvoDesign GPCR-I-TASSER BindProf BindProfX ResQ IonCom STRUM DAMpred

TM-score TM-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR NeBcon WDL-RF ATPbind DockRMSD

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP TM-fold DECOYS POTENTIAL RW/RWplus HPSF THE-DB CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13

You can:

GPCR

NameNociceptin receptor
SpeciesMus musculus (Mouse)
GeneOprl1
SynonymNOP receptor
NOP-r
NOPr
OP4
ORGC
[ Show all ]
DiseaseN/A for non-human GPCRs
Length367
Amino acid sequenceMESLFPAPFWEVLYGSHFQGNLSLLNETVPHHLLLNASHSAFLPLGLKVTIVGLYLAVCIGGLLGNCLVMYVILRHTKMKTATNIYIFNLALADTLVLLTLPFQGTDILLGFWPFGNALCKTVIAIDYYNMFTSTFTLTAMSVDRYVAICHPIRALDVRTSSKAQAVNVAIWALASVVGVPVAIMGSAQVEDEEIECLVEIPAPQDYWGPVFAICIFLFSFIIPVLIISVCYSLMIRRLRGVRLLSGSREKDRNLRRITRLVLVVVAVFVGCWTPVQVFVLVQGLGVQPGSETAVAILRFCTALGYVNSCLNPILYAFLDENFKACFRKFCCASALHREMQVSDRVRSIAKDVGLGCKTSETVPRPA
UniProtP35377
Protein Data BankN/A
GPCR-HGmod modelN/A
3D structure modelNo available structures or models
BioLiPN/A
Therapeutic Target DatabaseN/A
ChEMBLCHEMBL3621
IUPHAR320
DrugBankN/A

Known ligands

You can:

Total entries: 124
Page:  / 2 

GLASS IDMoleculeFormulaMolecular weightH-bond acceptor / donorXlogPLipinski's druglikeness
5554842D structureAc-RYYKWR-NH2C49H69N15O91012.1912 / 15-1.3No
5555022D structureDynorphin BC74H115N21O171570.8621 / 22-3.6No
5555102D structureAC1L1I54C26H27N3O4445.5196 / 33.5Yes
202022D structureCHEMBL412479C58H102N22O151347.5920 / 22-7.2No
5555622D structureBDBM85820C37H54N12O9810.91411 / 12-3.0No
227882D structureCHEMBL396972C80H130N28O211820.0926 / 30-8.1No
252182D structureCHEMBL428167C55H88N20O141253.4418 / 20-6.5No
5555972D structureMorphinan-3,6.alpha.-diol, 7,8-didehydro-4,5.alpha.-epoxy-17-methyl-C17H19NO3285.3434 / 20.8Yes
363832D structureCHEMBL262224C62H102N22O151395.6420 / 22-6.6No
487922D structureCID 53316770C79H126N26O191744.0423 / 27-4.8No
522292D structureBDBM50333103C90H143FN32O252092.3331 / 32-11.9No
524952D structureCHEMBL390658C82H136N28O211850.1726 / 30-7.4No
617542D structureCHEMBL394775C80H130N28O211820.0926 / 30-8.6No
5557322D structureDQCKKXVULJGBQN-UHFFFAOYSA-NC20H23NO4341.4075 / 21.9Yes
694642D structureCHEMBL263588C79H131FN28O201812.0927 / 28-9.0No
710732D structureCHEMBL403807C45H72N14O8937.16111 / 13-0.8No
826902D structureCID 100916438C79H130N28O211808.0845 / 332.1No
866032D structureCHEMBL541911C82H137ClN28O211886.6226 / 31N/ANo
907002D structureCHEMBL407461C61H102N22O151383.6321 / 23-7.1No
932512D structureCHEMBL405648C61H99ClN22O151416.0520 / 22-6.3No
933562D structureCHEMBL1631925C65H105N23O161464.721 / 23-7.1No
5558072D structureOFQ/N UFP-102C73H123FN28O171683.9625 / 27-8.8No
934992D structureCHEMBL410145C82H141N35O211953.2531 / 33-13.3No
992162D structureCHEMBL265544C62H99F3N22O151449.6123 / 22-6.1No
5558552D structureOFQ/N,Iodo[Tyr14]C82H126IN27O221968.9827 / 28-10.1No
1062902D structureUFP-112C83H139FN32O211940.2329 / 34-10.7No
1070282D structureCHEMBL411649C82H140FN35O211971.2432 / 33-13.2No
5558882D structureAC1MHXH5C40H43N3O6661.7998 / 53.2No
1194282D structureCHEMBL1631924C73H116N24O171601.8822 / 23-7.1No
5559582D structureAC1NB6STC26H35N5O6513.5957 / 60.2No
1262152D structureCHEMBL412537C61H99FN22O151399.621 / 22-6.9No
1264292D structureCHEMBL262928C61H101N23O151396.6221 / 23-7.7No
1424732D structureCHEMBL1631933C64H114N26O181535.7823 / 25-11.5No
1490232D structureCHEMBL394588C84H140N28O211878.2226 / 30-6.6No
1506502D structureCHEMBL406905C61H106N22O151387.6620 / 22-5.8No
1520182D structureCHEMBL410167C61H99IN22O151507.5120 / 22-6.3No
5560552D structureH-Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-Leu-Lys-Trp-Asp-Asn-Gln-OHC99H155N31O232147.5229 / 30-8.9No
1709542D structureCHEMBL317625C43H68N14O9925.10613 / 14-3.2No
1804352D structureCHEMBL410653C82H141N35O211953.2531 / 33-13.4No
5562072D structurealpha-NeoendorphinC60H89N15O131228.4617 / 16-2.1No
1832382D structureCHEMBL264846C79H129FN28O211826.0727 / 28-9.2No
1837332D structureBDBM50411363C83H140N32O211922.2428 / 31-11.9No
5542432D structureSCH 221510C28H31NO397.5622 / 16.0No
2007642D structure475150-69-7C27H35N3O2433.5964 / 13.3Yes
5562842D structure88373-73-3C30H39N5O7S2645.7910 / 7-0.6No
2036012D structureCHEMBL411168C62H102N22O151395.6420 / 22-6.6No
2103722D structureCID 49850694C87H139N31O242003.2629 / 33-10.9No
2153092D structureCHEMBL414782C82H140FN35O211971.2432 / 33-13.3No
2153232D structureCHEMBL232245C82H136N28O211850.1726 / 30-7.4No
2154452D structureCHEMBL414963C62H104N22O141381.6520 / 22-6.3No
2199022D structureCHEMBL438398C82H136N28O211850.1726 / 30-7.3No
2238612D structureCHEMBL412606C61H100N22O161397.6121 / 23-7.3No
2240362D structureCHEMBL556556C82H137ClN28O211886.6226 / 31N/ANo
2267372D structure[Nphe1]nociceptin(1-13)NH2C61H100N22O151381.6120 / 22-7.0No
2313052D structureCHEMBL427699C81H134N28O211836.1426 / 30-7.9No
5563892D structureCID 102330627C82H127N27O231859.0846 / 33-0.4No
2368952D structureCHEMBL257921C49H72N14O8985.20511 / 130.4No
2406842D structureCHEMBL261997C61H99FN22O151399.621 / 22-6.9No
5564132D structureCHEMBL353979C26H35NO4425.5695 / 23.6Yes
2434092D structureCHEMBL438234C61H106N22O151387.6620 / 22-6.1No
2438152D structureCHEMBL415583C62H102N22O161411.6421 / 22-7.0No
2454262D structureCHEMBL234724C83H136N28O211862.1826 / 30-7.4No
2457122D structureCID 49850693C79H128N26O181730.0623 / 27-4.7No
2466182D structureCHEMBL51556C43H66N14O10939.08913 / 14-3.5No
2502092D structureCHEMBL413178C62H102N22O151395.6420 / 22-6.6No
5564482D structureMorphinan-3-ol, 17-(2-propenyl)-C19H25NO283.4152 / 13.5Yes
5564922D structurefentanylC22H28N2O336.4792 / 04.0Yes
2629562D structureCHEMBL268394C83H136N28O211862.1826 / 30-6.8No
2640382D structureCID 53325329C82H136FN29O211883.1728 / 31-8.7No
2656162D structureCHEMBL398224C82H136N28O211850.1726 / 30-7.3No
2691792D structureBDBM21842C79H129N27O221809.0727 / 28-11.0No
2693222D structureD07WQGC79H128N26O231810.0528 / 28-12.6No
2701902D structureNociceptin(1-12)-NH2C55H88N20O141253.4418 / 20-6.5No
2726302D structureCHEMBL415781C82H134N28O211848.1526 / 30-7.9No
2751812D structureCHEMBL233069C80H132N28O211822.1126 / 30-8.4No
2755052D structureCHEMBL437192C84H140N28O211878.2226 / 30-6.6No
2782722D structureCHEMBL437744C84H142FN33O211969.2730 / 32-12.7No
2782782D structureCHEMBL2372052C84H142FN33O211969.2730 / 35-11.6No
2848982D structureCID 49850695C90H145FN32O242078.3531 / 34-11.0No
2856752D structureBDBM50333106C91H149N33O262121.431 / 33-13.9No
2953402D structureCHEMBL1631929C61H98N22O161395.5920 / 22-7.0No
2963152D structurenociceptin(1-13)NH2C61H100N22O151381.6120 / 22-7.0No
2994082D structureCHEMBL428668C61H99FN22O151399.621 / 22-6.9No
3013132D structureCHEMBL442297C82H142FN35O201957.2632 / 33-13.0No
5566782D structureAc-Arg-Tyr-Tyr-Arg-Trp-Arg-NH(2)C49H69N17O91040.212 / 16-2.3No
3074752D structureCHEMBL2372364C81H135ClN28O211872.626 / 31N/ANo
3121512D structureCHEMBL411621C79H130N28O211808.0826 / 28-9.3No
3235762D structureCHEMBL262544C82H143N35O201939.2731 / 33-13.1No
5568072D structureBDBM85823C55H79IN16O121283.2415 / 16-1.7No
3381352D structureCHEMBL436819C82H134N28O211848.1526 / 30-7.4No
3405772D structureCHEMBL263859C55H90N20O131239.4518 / 20-6.2No
3413692D structureCHEMBL406097C61H99BrN22O151460.5120 / 22-6.3No
5568892D structureLeu-enkephalinC28H37N5O7555.6327 / 6-0.5No
3465782D structureCHEMBL1631932C59H106N22O151363.6419 / 21-6.5No
3472732D structureCHEMBL1783826C26H33Cl2N3O474.473 / 15.5No
5569082D structureNaloxone(-)C19H21NO4327.385 / 22.1Yes
3518322D structureCHEMBL427791C62H99N23O151406.6221 / 22-7.3No
3543992D structureCHEMBL429363C61H100N22O161397.6121 / 23-7.3No
3566962D structureH-FGGFTGARKSARKAANQA-NH2C79H129N29O221837.0827 / 29-10.9No
5569752D structureFortalgesicC19H27NO285.4312 / 13.3Yes

yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218