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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3703203
Molecular formula	C32H37FN2O6
IUPAC name	2-[4-[3-(4-fluorophenoxy)-5-[[4-hydroxy-4-(2-methylpropyl)piperidine-1-carbonyl]amino]phenoxy]phenyl]-2-methylpropanoic acid
Molecular weight	564.654
Hydrogen bond acceptor	7
Hydrogen bond donor	3
XlogP	6.0
Synonyms	US8975409, Example 9 BDBM149712 MBTKFRQXHPGCLC-UHFFFAOYSA-N SCHEMBL14839446 2-{4-[3-(4-fluorophenoxy)-5-{[(4-hydroxy-4-isobutyl-1-piperidinyl)carbonyl]amino}phenoxy]phenyl}-2-methylpropanoic acid
Inchi Key	MBTKFRQXHPGCLC-UHFFFAOYSA-N
Inchi ID	InChI=1S/C32H37FN2O6/c1-21(2)20-32(39)13-15-35(16-14-32)30(38)34-24-17-27(19-28(18-24)41-26-11-7-23(33)8-12-26)40-25-9-5-22(6-10-25)31(3,4)29(36)37/h5-12,17-19,21,39H,13-16,20H2,1-4H3,(H,34,38)(H,36,37)
PubChem CID	71547556
ChEMBL	CHEMBL3703203
IUPHAR	N/A
BindingDB	149712
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
201634	Sphingosine 1-phosphate receptor 2	O95136	S1PR2	Homo sapiens (Human)	353
460994	Sphingosine 1-phosphate receptor 2	P47752	S1pr2	Rattus norvegicus (Rat)	352

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