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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	Befiradol
Molecular formula	C20H22ClF2N3O
IUPAC name	(3-chloro-4-fluorophenyl)-[4-fluoro-4-[[(5-methylpyridin-2-yl)methylamino]methyl]piperidin-1-yl]methanone
Molecular weight	393.863
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	3.2
Synonyms	(3-Chloro-4-fluoro-phenyl)-(4-fluoro-4-{[(5-methyl-pyridin-2-ylmethyl)-amino]-methyl}-piperidin-1-yl)-methanone BDBM50328639 F-13640 UNII-RAT9OHA1YH 110B649 HY-14785 D0E1PL RAT9OHA1YH (3-chloro-4-fluorophenyl)(4-fluoro-4-(((5-methylpyridin-2-yl)methylamino)methyl)piperidin-1-yl)methanone F13640 [3H]F13640 208110-64-9 CHEMBL45305 L001676 AKOS032954037 F 13640 SCHEMBL678174 (3-chloro-4-fluorophenyl)-[4-fluoro-4-[[(5-methylpyridin-2-yl)methylamino]methyl]piperidin-1-yl]methanone Befiradol [INN] GTPL3925 [3H]NLX-112 CS-0003559 NLX-112 [ Show all ]
Inchi Key	PKZXLMVXBZICTF-UHFFFAOYSA-N
Inchi ID	InChI=1S/C20H22ClF2N3O/c1-14-2-4-16(25-11-14)12-24-13-20(23)6-8-26(9-7-20)19(27)15-3-5-18(22)17(21)10-15/h2-5,10-11,24H,6-9,12-13H2,1H3
PubChem CID	9865384
ChEMBL	CHEMBL45305
IUPHAR	3925
BindingDB	50328639
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
262383	5-hydroxytryptamine receptor 1A	P08908	HTR1A	Homo sapiens (Human)	422
262385	5-hydroxytryptamine receptor 1A	P19327	Htr1a	Rattus norvegicus (Rat)	422
262384	5-hydroxytryptamine receptor 2A	P50129	HTR2A	Sus scrofa (Pig)	470
262387	D(1A) dopamine receptor	P50130	DRD1	Sus scrofa (Pig)	446
262386	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
262382	D(3) dopamine receptor	P35462	DRD3	Homo sapiens (Human)	400
529048	D(4) dopamine receptor	P21917	DRD4	Homo sapiens (Human)	467

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