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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL3359522
Molecular formula	C24H23ClN2O4
IUPAC name	2-[(3R)-4-chloro-6-[(3-cyano-4-propan-2-yloxyphenyl)methoxy]-2,3-dihydro-1H-pyrrolo[1,2-a]indol-3-yl]acetic acid
Molecular weight	438.908
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	4.2
Synonyms	BDBM50041982 SCHEMBL2019826
Inchi Key	RWFBHHNEDFDSPE-MRXNPFEDSA-N
Inchi ID	InChI=1S/C24H23ClN2O4/c1-14(2)31-21-6-3-15(9-17(21)12-26)13-30-18-4-5-20-19(11-18)23(25)24-16(10-22(28)29)7-8-27(20)24/h3-6,9,11,14,16H,7-8,10,13H2,1-2H3,(H,28,29)/t16-/m1/s1
PubChem CID	67250226
ChEMBL	CHEMBL3359522
IUPHAR	N/A
BindingDB	50041982
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
453857	Sphingosine 1-phosphate receptor 1	O08530	S1pr1	Mus musculus (Mouse)	382
453858	Sphingosine 1-phosphate receptor 1	P21453	S1PR1	Homo sapiens (Human)	382
453862	Sphingosine 1-phosphate receptor 1	P48303	S1pr1	Rattus norvegicus (Rat)	383
453863	Sphingosine 1-phosphate receptor 2	O95136	S1PR2	Homo sapiens (Human)	353
453860	Sphingosine 1-phosphate receptor 3	Q99500	S1PR3	Homo sapiens (Human)	378
453861	Sphingosine 1-phosphate receptor 4	O95977	S1PR4	Homo sapiens (Human)	384
453859	Sphingosine 1-phosphate receptor 5	Q9H228	S1PR5	Homo sapiens (Human)	398

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