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Ligand

NameCHEMBL1929548
Molecular formulaC22H28F3NO3S
IUPAC name7-[(2R)-2-[(E,3S)-3-hydroxy-4-[3-(trifluoromethyl)phenyl]but-1-enyl]-5-sulfanylidenepyrrolidin-1-yl]heptanoic acid
Molecular weight443.525
Hydrogen bond acceptor7
Hydrogen bond donor2
XlogP4.0
SynonymsSCHEMBL4902081
BDBM50360155
Inchi KeySLVHGRRYWCUFLN-AYLUNBTKSA-N
Inchi IDInChI=1S/C22H28F3NO3S/c23-22(24,25)17-7-5-6-16(14-17)15-19(27)11-9-18-10-12-20(30)26(18)13-4-2-1-3-8-21(28)29/h5-7,9,11,14,18-19,27H,1-4,8,10,12-13,15H2,(H,28,29)/b11-9+/t18-,19+/m0/s1
PubChem CID11744126
ChEMBLCHEMBL1929548
IUPHARN/A
BindingDB50360155
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

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Total entries: 5
Page:  / 1 

GLASS IDNameUniProtGeneSpeciesLength
317527Prostaglandin E2 receptor EP1 subtypeP35375Ptger1Mus musculus (Mouse)405
317526Prostaglandin E2 receptor EP2 subtypeQ62053Ptger2Mus musculus (Mouse)362
317529Prostaglandin E2 receptor EP3 subtypeP30557Ptger3Mus musculus (Mouse)365
317525Prostaglandin E2 receptor EP4 subtypeP43114Ptger4Rattus norvegicus (Rat)488
317528Prostaglandin E2 receptor EP4 subtypeP32240Ptger4Mus musculus (Mouse)513

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