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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	Racemic DOTFM
Molecular formula	C12H16F3NO2
IUPAC name	1-[2,5-dimethoxy-4-(trifluoromethyl)phenyl]propan-2-amine
Molecular weight	263.26
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	2.8
Synonyms	CHEMBL6620 2,5-dimethoxy-4-trifluoromethylamphetamine DTXSID40439330 BDBM50038370 D08VLD 2-(2,5-Dimethoxy-4-trifluoromethyl-phenyl)-1-methyl-ethylamine 159277-07-3 DOTFM SCHEMBL14655679 [ Show all ]
Inchi Key	WPGOTSORDNBMHP-UHFFFAOYSA-N
Inchi ID	InChI=1S/C12H16F3NO2/c1-7(16)4-8-5-11(18-3)9(12(13,14)15)6-10(8)17-2/h5-7H,4,16H2,1-3H3
PubChem CID	10400521
ChEMBL	CHEMBL6620
IUPHAR	N/A
BindingDB	50038370
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
379003	5-hydroxytryptamine receptor 1A	P19327	Htr1a	Rattus norvegicus (Rat)	422
378999	5-hydroxytryptamine receptor 2A	P14842	Htr2a	Rattus norvegicus (Rat)	471
379002	5-hydroxytryptamine receptor 2A	P35363	Htr2a	Mus musculus (Mouse)	471
379000	5-hydroxytryptamine receptor 2C	P08909	Htr2c	Rattus norvegicus (Rat)	460
379001	5-hydroxytryptamine receptor 2C	P34968	Htr2c	Mus musculus (Mouse)	459

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