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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	JNJ-39758979
Molecular formula	C11H19N5
IUPAC name	4-[(3R)-3-aminopyrrolidin-1-yl]-6-propan-2-ylpyrimidin-2-amine
Molecular weight	221.308
Hydrogen bond acceptor	5
Hydrogen bond donor	2
XlogP	0.7
Synonyms	4-[(3R)-3-aminopyrrolidin-1-yl]-6-propan-2-ylpyrimidin-2-amine CS-0020957 MolPort-044-723-874 JNJ 39758979 UNII-5RV7T5BNMG 1046447-90-8 JNL-39758979 GTPL8984 SB16804 AKOS030628488 ZINC114197058 2-Pyrimidinamine, 4-((3R)-3-amino-1-pyrrolidinyl)-6-(1-methylethyl)- CHEMBL3236549 KS-0000063V 5RV7T5BNMG HY-101189 SCHEMBL604514 (r)-4-(3-amino-pyrrolidin-1-yl)-6-isopropyl-pyrimidin-2-ylamine BDBM50006789 jnj39758979 [ Show all ]
Inchi Key	COOGVHJHSCBOQT-MRVPVSSYSA-N
Inchi ID	InChI=1S/C11H19N5/c1-7(2)9-5-10(15-11(13)14-9)16-4-3-8(12)6-16/h5,7-8H,3-4,6,12H2,1-2H3,(H2,13,14,15)/t8-/m1/s1
PubChem CID	24994634
ChEMBL	CHEMBL3236549
IUPHAR	8984
BindingDB	50006789
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
553465	Histamine H1 receptor	P35367	HRH1	Homo sapiens (Human)	487
553466	Histamine H2 receptor	P25021	HRH2	Homo sapiens (Human)	359
46824	Histamine H3 receptor	Q9Y5N1	HRH3	Homo sapiens (Human)	445
46822	Histamine H4 receptor	Q91ZY1	Hrh4	Rattus norvegicus (Rat)	391
46823	Histamine H4 receptor	Q91ZY2	Hrh4	Mus musculus (Mouse)	391
46825	Histamine H4 receptor	Q9H3N8	HRH4	Homo sapiens (Human)	390

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