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Ligand

NameMLS000374746
Molecular formulaC20H18Cl2N4O4S
IUPAC name4,5-dichloro-2-[2-(4-naphthalen-2-ylsulfonylpiperazin-1-yl)-2-oxoethyl]pyridazin-3-one
Molecular weight481.348
Hydrogen bond acceptor6
Hydrogen bond donor0
XlogP2.5
SynonymsSMR000242163
4,5-dichloro-2-[2-(4-naphthalen-2-ylsulfonylpiperazin-1-yl)-2-oxoethyl]pyridazin-3-one
ZINC03464696
AC1M9KUF
MLS002633117
[ Show all ]
Inchi KeyDOIOALQHSXBINK-UHFFFAOYSA-N
Inchi IDInChI=1S/C20H18Cl2N4O4S/c21-17-12-23-26(20(28)19(17)22)13-18(27)24-7-9-25(10-8-24)31(29,30)16-6-5-14-3-1-2-4-15(14)11-16/h1-6,11-12H,7-10,13H2
PubChem CID2585042
ChEMBLCHEMBL1540377
IUPHARN/A
BindingDB42060
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

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Total entries: 8
Page:  / 1 

GLASS IDNameUniProtGeneSpeciesLength
65003Galanin receptor type 2O43603GALR2Homo sapiens (Human)387
65004Glucagon-like peptide 1 receptorP43220GLP1RHomo sapiens (Human)463
65008Lutropin-choriogonadotropic hormone receptorP22888LHCGRHomo sapiens (Human)699
65005Neuropeptide S receptorQ6W5P4NPSR1Homo sapiens (Human)371
470937Parathyroid hormone/parathyroid hormone-related peptide receptorQ03431PTH1RHomo sapiens (Human)593
65002Sphingosine 1-phosphate receptor 1P21453S1PR1Homo sapiens (Human)382
65006Sphingosine 1-phosphate receptor 4O95977S1PR4Homo sapiens (Human)384
65007Thyrotropin receptorP16473TSHRHomo sapiens (Human)764

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