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Ligand

NameCHEMBL1957436
Molecular formulaC26H25ClN2O4S2
IUPAC name2-[2-[(2R)-2-[(E,3S)-4-[3-(4-chlorophenyl)phenyl]-3-hydroxybut-1-enyl]-5-oxopyrrolidin-1-yl]ethylsulfanyl]-1,3-thiazole-4-carboxylic acid
Molecular weight529.066
Hydrogen bond acceptor7
Hydrogen bond donor2
XlogP5.1
SynonymsBDBM50366137
SCHEMBL10210673
Inchi KeyFZLGDIHXQOETBY-PCBIHFGQSA-N
Inchi IDInChI=1S/C26H25ClN2O4S2/c27-20-6-4-18(5-7-20)19-3-1-2-17(14-19)15-22(30)10-8-21-9-11-24(31)29(21)12-13-34-26-28-23(16-35-26)25(32)33/h1-8,10,14,16,21-22,30H,9,11-13,15H2,(H,32,33)/b10-8+/t21-,22+/m0/s1
PubChem CID57384034
ChEMBLCHEMBL1957436
IUPHARN/A
BindingDB50366137
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand is heavier than 500 daltons.
This ligand has a partition coefficient log P greater than 5.

Known GPCRs

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Total entries: 6
Page:  / 1 

GLASS IDNameUniProtGeneSpeciesLength
91019Prostaglandin E2 receptor EP1 subtypeP35375Ptger1Mus musculus (Mouse)405
91017Prostaglandin E2 receptor EP2 subtypeQ62928Ptger2Rattus norvegicus (Rat)357
91018Prostaglandin E2 receptor EP2 subtypeQ62053Ptger2Mus musculus (Mouse)362
91020Prostaglandin E2 receptor EP3 subtypeP30557Ptger3Mus musculus (Mouse)365
91016Prostaglandin E2 receptor EP4 subtypeP32240Ptger4Mus musculus (Mouse)513
91021Prostaglandin E2 receptor EP4 subtypeP43114Ptger4Rattus norvegicus (Rat)488

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