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Ligand

NameSkf-81297
Molecular formulaC16H16ClNO2
IUPAC name9-chloro-5-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol
Molecular weight289.759
Hydrogen bond acceptor3
Hydrogen bond donor3
XlogP2.7
Synonyms1H-3-Benzazepine-7,8-diol, 6-chloro-2,3,4,5-tetrahydro-1-phenyl-
1H-3-Benzazepine-7,8-diol,6-chloro-2,3,4,5-tetrahydro-1-phenyl-
6-chloro-1-phenyl-2,3,4,5-tetrahydro-1h-3-benzazepine-7,8-diol
6-Chloro-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol
6-Chloro-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol; hydrobromide
[ Show all ]
Inchi KeyGHWJEDJMOVUXEC-UHFFFAOYSA-N
Inchi IDInChI=1S/C16H16ClNO2/c17-15-11-6-7-18-9-13(10-4-2-1-3-5-10)12(11)8-14(19)16(15)20/h1-5,8,13,18-20H,6-7,9H2
PubChem CID1218
ChEMBLCHEMBL353335
IUPHAR938
BindingDB86282
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

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Total entries: 10
Page:  / 1 

GLASS IDNameUniProtGeneSpeciesLength
968565-hydroxytryptamine receptor 1AP08908HTR1AHomo sapiens (Human)422
5558325-hydroxytryptamine receptor 2AP14842Htr2aRattus norvegicus (Rat)471
96862Alpha-2C adrenergic receptorP22086Adra2cRattus norvegicus (Rat)458
96855D(1A) dopamine receptorP21728DRD1Homo sapiens (Human)446
96857D(1A) dopamine receptorP18901Drd1Rattus norvegicus (Rat)446
96861D(2) dopamine receptorP14416DRD2Homo sapiens (Human)443
555831D(2) dopamine receptorP61169Drd2Rattus norvegicus (Rat)444
96860D(3) dopamine receptorP35462DRD3Homo sapiens (Human)400
96859Galanin receptor type 3O60755GALR3Homo sapiens (Human)368
96858Trace amine-associated receptor 1Q96RJ0TAAR1Homo sapiens (Human)339

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