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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	MLS000417430
Molecular formula	C20H18ClN3O4S
IUPAC name	1-(3-chlorophenyl)-3-[3-[(2-methoxyphenyl)sulfamoyl]phenyl]urea
Molecular weight	431.891
Hydrogen bond acceptor	5
Hydrogen bond donor	3
XlogP	3.4
Synonyms	ZINC8686943 1-(3-chlorophenyl)-3-{3-[(2-methoxyphenyl)sulfamoyl]phenyl}urea cid_4178848 AC1N4H9Q STK964786 3-{[(3-chlorophenyl)carbamoyl]amino}-N-(2-methoxyphenyl)benzenesulfonamide HMS2514O18 AKOS024300287 MolPort-002-357-874 Z44591569 1-(3-chlorophenyl)-3-[3-[(2-methoxyphenyl)sulfamoyl]phenyl]urea CHEMBL1517625 380332-63-8 MCULE-2600092377 BDBM95734 SMR000242621 [ Show all ]
Inchi Key	IYTDIHBYTAIGOJ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C20H18ClN3O4S/c1-28-19-11-3-2-10-18(19)24-29(26,27)17-9-5-8-16(13-17)23-20(25)22-15-7-4-6-14(21)12-15/h2-13,24H,1H3,(H2,22,23,25)
PubChem CID	4178848
ChEMBL	CHEMBL1517625
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
144994	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463
144991	Lutropin-choriogonadotropic hormone receptor	P22888	LHCGR	Homo sapiens (Human)	699
144992	Neuropeptide S receptor	Q6W5P4	NPSR1	Homo sapiens (Human)	371
144993	Thyrotropin receptor	P16473	TSHR	Homo sapiens (Human)	764

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