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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	granisetron
Molecular formula	C18H24N4O
IUPAC name	1-methyl-N-(9-methyl-9-azabicyclo[3.3.1]nonan-3-yl)indazole-3-carboxamide
Molecular weight	312.417
Hydrogen bond acceptor	3
Hydrogen bond donor	1
XlogP	2.8
Synonyms	TC-063582 1-Methyl-1H-indazole-3-carboxylic acid (9-methyl-9-aza-bicyclo[3.3.1]non-3-yl)-amide(Granisetron) 1364914-39-5 AC1L1G3K C18H24N4O exo-Granisetron (Granisetron Impurity F) GTPL2292 N-(9-Methyl-9-azabicyclo[3.3.1]nonan-3-yl)-1-methyl-1H-indazole-3-carboxamide [3H]GRANISETRON (BRL 43694)1-Methyl-1H-indazole-3-carboxylic acid (9-methyl-9-aza-bicyclo[3.3.1]non-3-yl)-amide 1-methyl-N-(9-methyl-9-azabicyclo[3.3.1]non-3-yl)-indazole-3-carboxamide BCP10022 CHEMBL519643 Granisetron HCl KB-272637 PDSP2_001250 SCHEMBL445223 1-Methyl-1H-indazole-3-carboxylic acid (9-methyl-9-aza-bicyclo[3.3.1]non-3-yl)-amide 109889-09-0 AB01274752_02 BRL 43964 D0P2HR Granisetron-d3 MCULE-2474398583 [3H]-BRL-43694 1-methyl-N-((1S,5R)-9-methyl-9-aza-bicyclo[3.3.1]nonan-3-yl)-1H-indazole-3-carboxamide 1H-Indazole-3-carboxamide, 1-methyl-N-(9-methyl-9-azabicyclo(3.3.1)non-3-yl)-, endo- AC1Q5GMW HY-B0071 NCGC00186041-01 RTC-063582 (granisetron)1-Methyl-1H-indazole-3-carboxylic acid (8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl)-amide 1-methyl-N-(9-methyl-9-azabicyclo[3.3.1]nonan-3-yl)indazole-3-carboxamide AB0073059 BDBM50000483 CS-1509 Granisetron Monohydrochloride L000281 STL483411 1-Methyl-1H-indazole-3-carboxylic acid (9-methyl-9-aza-bicyclo[3.3.1]non-3-yl)-amide(BRL 43694) 124998-65-8 AB01274752_03 BRL-43694A EX-A1291 Granisetronum [INN-Latin] MFWNKCLOYSRHCJ-UHFFFAOYSA-N [3H]-granisetron 1-methyl-n-(9-methyl-9-azabicyclo[3.3.1]non-3-yl)-1h-indazole-3-carboxamide 2-(9-Methyl-3,9-diaza-bicyclo[3.3.1]non-3-yl)-1-(1-methyl-1H-indol-3-yl)-ethanone(Granisetron) AKOS015895362 CHEMBL289469 Granisetron base I06-0732 PDSP1_001266 SC-15163 1-Methyl-1H-indazole-3-carboxylic acid (8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl)-amide 1-methyl-N-(9-methyl-9-azabicyclo[3.3.1]nonan-7-yl)indazole-3-carboxamide AB01274752-01 BRL 43694 CTK8E8433 Granisetron [USAN:BAN:INN] LS-172104 [ Show all ]
Inchi Key	MFWNKCLOYSRHCJ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C18H24N4O/c1-21-13-6-5-7-14(21)11-12(10-13)19-18(23)17-15-8-3-4-9-16(15)22(2)20-17/h3-4,8-9,12-14H,5-7,10-11H2,1-2H3,(H,19,23)
PubChem CID	3510
ChEMBL	CHEMBL289469
IUPHAR	N/A
BindingDB	50000483
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
204458	5-hydroxytryptamine receptor 1A	P19327	Htr1a	Rattus norvegicus (Rat)	422
204459	5-hydroxytryptamine receptor 1B	P28564	Htr1b	Rattus norvegicus (Rat)	386
204457	5-hydroxytryptamine receptor 1D	P28565	Htr1d	Rattus norvegicus (Rat)	374
204456	5-hydroxytryptamine receptor 2C	P08909	Htr2c	Rattus norvegicus (Rat)	460
204454	5-hydroxytryptamine receptor 4	Q62758	Htr4	Rattus norvegicus (Rat)	406
204455	5-hydroxytryptamine receptor 4	O70528	HTR4	Cavia porcellus (Guinea pig)	388
556293	5-hydroxytryptamine receptor 7	P32305	Htr7	Rattus norvegicus (Rat)	448
204453	D(2) dopamine receptor	P61169	Drd2	Rattus norvegicus (Rat)	444

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