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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL1923292
Molecular formula	C19H21FN2O2
IUPAC name	1-(2,3-dihydro-1,4-benzodioxin-6-yl)-4-[(4-fluorophenyl)methyl]piperazine
Molecular weight	328.387
Hydrogen bond acceptor	5
Hydrogen bond donor	0
XlogP	3.2
Synonyms	SCHEMBL7527827 1-(1,4 benzodioxan-6-yl)-4-(4-fluorobenzyl) piperazine BDBM50358838 OEFFTIMBYVFOPK-UHFFFAOYSA-N 1-(1,4 benzodioxan-6-yl)-4-(4-fluorobenzyl)piperazine
Inchi Key	OEFFTIMBYVFOPK-UHFFFAOYSA-N
Inchi ID	InChI=1S/C19H21FN2O2/c20-16-3-1-15(2-4-16)14-21-7-9-22(10-8-21)17-5-6-18-19(13-17)24-12-11-23-18/h1-6,13H,7-12,14H2
PubChem CID	9797495
ChEMBL	CHEMBL1923292
IUPHAR	N/A
BindingDB	50358838
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
239080	5-hydroxytryptamine receptor 2A	P50129	HTR2A	Sus scrofa (Pig)	470
239077	D(1A) dopamine receptor	P50130	DRD1	Sus scrofa (Pig)	446
239078	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
239079	D(3) dopamine receptor	P35462	DRD3	Homo sapiens (Human)	400
528390	D(4) dopamine receptor	P21917	DRD4	Homo sapiens (Human)	467

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