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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	MLS003171622
Molecular formula	C22H16ClN3O3
IUPAC name	N-[3-chloro-4-(2,5-dioxo-3-phenylpyrrolidin-1-yl)phenyl]pyridine-2-carboxamide
Molecular weight	405.838
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	3.1
Synonyms	SCHEMBL1895793 CHEMBL1698322 SMR001875507 CHEBI:91771
Inchi Key	UYGDCIXFYIWDMR-UHFFFAOYSA-N
Inchi ID	InChI=1S/C22H16ClN3O3/c23-17-12-15(25-21(28)18-8-4-5-11-24-18)9-10-19(17)26-20(27)13-16(22(26)29)14-6-2-1-3-7-14/h1-12,16H,13H2,(H,25,28)
PubChem CID	45110765
ChEMBL	CHEMBL1698322
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
348637	Metabotropic glutamate receptor 4	P31423	Grm4	Rattus norvegicus (Rat)	912
348638	Metabotropic glutamate receptor 4	Q14833	GRM4	Homo sapiens (Human)	912
348640	Metabotropic glutamate receptor 5	P31424	Grm5	Rattus norvegicus (Rat)	1203
348642	Metabotropic glutamate receptor 6	P35349	Grm6	Rattus norvegicus (Rat)	871
348639	Metabotropic glutamate receptor 7	P35400	Grm7	Rattus norvegicus (Rat)	915
348641	Metabotropic glutamate receptor 8	P70579	Grm8	Rattus norvegicus (Rat)	908

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