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GPCR-RD is a database for experimental restaints of GPCRs. Although no solved X-ray or NMR structure is available for most GPCR sequences, numerous experiments have been performed on GPCRs to identify the critical residues and motifs. Experimental restraints were systematically collected from the literature using an automated text mining algorithm combined with manual validation, with the purpose of assisting GPCR 3-D structure modeling and function annotation. The GPCR-RD data are useful for GPCR 3D structure modeling, such as the GPCR-I-TASSER algorithm. The flow chart below summarizes the procedure for the extraction of experimental data and spatial restraints from literature and other resources.

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11002 entries in GPCR-RD.
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GPCR-RD: GPCR experimental restaint database
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Swiss-Prot ID Experimental Data Swiss-Prot ID Experimental Data Swiss-Prot ID Experimental Data
lshr_pig N312S lshr_pig C343S lshr_pig E354K
lshr_pig D564G lshr_pig A568V lshr_pig M571I
lshr_rat L12C lshr_rat E28C lshr_rat E28M
lshr_rat E28N lshr_rat C34S lshr_rat C38A
lshr_rat C38S lshr_rat C40S lshr_rat L46
lshr_rat L46A lshr_rat C48 lshr_rat C48A
lshr_rat C48S lshr_rat G50 lshr_rat G50A
lshr_rat P51R lshr_rat K66D lshr_rat K66R
lshr_rat V79M lshr_rat K81D lshr_rat K81R
lshr_rat E83K lshr_rat E91K lshr_rat E94K
lshr_rat N103Q lshr_rat S105A lshr_rat E106K
lshr_rat K130D lshr_rat K147D lshr_rat E158K
lshr_rat D161K lshr_rat N178Q lshr_rat S180A
lshr_rat K184E lshr_rat K184G lshr_rat K184Q
lshr_rat K184R lshr_rat N199Q lshr_rat T201A
lshr_rat E207K lshr_rat K209E lshr_rat K209G
lshr_rat K209Q lshr_rat K209R lshr_rat E210K
lshr_rat E210N lshr_rat E215K lshr_rat K216E
lshr_rat D232E lshr_rat D232K lshr_rat D232Q
lshr_rat K261D lshr_rat T276K lshr_rat C283S
lshr_rat C284S lshr_rat N295 lshr_rat N303
lshr_rat C308S lshr_rat N317 lshr_rat S322
lshr_rat Y337A lshr_rat C340S lshr_rat C347S
lshr_rat D352A lshr_rat D352K lshr_rat F354A
lshr_rat F354Y lshr_rat N355A lshr_rat P356A
lshr_rat P356D lshr_rat C357A lshr_rat C357R
lshr_rat C357S lshr_rat E358A lshr_rat E358D
lshr_rat E358K lshr_rat D359A lshr_rat D359E
lshr_rat D359K lshr_rat I360V lshr_rat M361A
lshr_rat G362A lshr_rat G362F lshr_rat Y363
lshr_rat Y363D lshr_rat Y363F lshr_rat R367E


Reference:

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