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BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP TM-fold DECOYS POTENTIAL RW/RWplus HPSF THE-DB CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13

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GPCR

NameAlpha-1D adrenergic receptor
SpeciesRattus norvegicus (Rat)
GeneAdra1d
SynonymAlpha-1A adrenergic receptor
RA42
alpha1D-adrenoceptor
Alpha-1D adrenoreceptor
ADRA1A
[ Show all ]
DiseaseN/A for non-human GPCRs
Length561
Amino acid sequenceMTFRDILSVTFEGPRSSSSTGGSGAGGGAGTVGPEGGAVGGVPGATGGGAVVGTGSGEDNQSSTGEPGAAASGEVNGSAAVGGLVVSAQGVGVGVFLAAFILTAVAGNLLVILSVACNRHLQTVTNYFIVNLAVADLLLSAAVLPFSATMEVLGFWAFGRTFCDVWAAVDVLCCTASILSLCTISVDRYVGVRHSLKYPAIMTERKAAAILALLWAVALVVSVGPLLGWKEPVPPDERFCGITEEVGYAIFSSVCSFYLPMAVIVVMYCRVYVVARSTTRSLEAGIKREPGKASEVVLRIHCRGAATSAKGYPGTQSSKGHTLRSSLSVRLLKFSREKKAAKTLAIVVGVFVLCWFPFFFVLPLGSLFPQLKPSEGVFKVIFWLGYFNSCVNPLIYPCSSREFKRAFLRLLRCQCRRRRRRLWAVYGHHWRASTGDARSDCAPSPRIAPPGAPLALTAHPGAGSADTPETQDSVSSSRKPASALREWRLLGPLQRPTTQLRAKVSSLSHKIRSGARRAETACALRSEVEAVSLNVPQDGAEAVICQAYEPGDYSNLRETDI
UniProtP23944
Protein Data BankN/A
GPCR-HGmod modelN/A
3D structure modelNo available structures or models
BioLiPN/A
Therapeutic Target DatabaseN/A
ChEMBLCHEMBL326
IUPHAR24
DrugBankN/A

Known ligands

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Total entries: 805
Page:  / 9 

GLASS IDMoleculeFormulaMolecular weightH-bond acceptor / donorXlogPLipinski's druglikeness
11292D structureCHEMBL287965C24H24N4O3S448.5416 / 13.1Yes
16372D structureCHEMBL1259079C26H28N2S400.5843 / 05.7No
21132D structureCHEMBL91326C24H34N4O2410.5625 / 14.2Yes
30372D structureCHEMBL1255085C23H25NO5395.4556 / 33.9Yes
4418512D structureCHEMBL3342860C27H32F3N3O4519.5659 / 03.9No
42822D structureCHEMBL65846C18H16N2O3308.3374 / 11.7Yes
45062D structureCHEMBL215151C24H26ClNO4427.9255 / 2N/AN/A
47332D structurelipoic acidC8H14O2S2206.3184 / 11.7Yes
68412D structureCHEMBL1259231C23H26N4S390.5494 / 03.7Yes
4420242D structureCHEMBL3342852C19H28N2O3S364.5046 / 02.5Yes
81172D structureCHEMBL317333C26H24FN5425.5115 / 04.0Yes
83142D structureCHEMBL1259080C27H30N2S414.6113 / 06.1No
84552D structureCHEMBL208355C21H14ClN3O3391.8114 / 04.8Yes
86412D structureCHEMBL55629C22H27F3N4O3452.4788 / 12.9Yes
5361982D structureCHEMBL27021C19H24N2O296.4143 / 03.8Yes
87832D structureCHEMBL220515C24H26ClN5O2451.9555 / 13.6Yes
89012D structureEthanesulfonamide, N-[3-(3-pyrrolidinyl)phenyl]-C12H18N2O2S254.3484 / 21.0Yes
100462D structureAbanoquilC22H25N3O4395.4597 / 13.4Yes
104422D structureSB 204070 hydrochlorideC19H27ClN2O4382.8856 / 13.5Yes
107782D structureCHEMBL1242445C26H33N3O4451.5676 / 02.4Yes
107882D structureCHEMBL1242444C26H33N3O4451.5676 / 02.4Yes
4421332D structureCHEMBL3415012C24H30N4O2406.534 / 23.2Yes
111012D structureCHEMBL2261352C14H18N4O2274.3243 / 40.0Yes
112762D structureCHEMBL1946783C31H34N2O6530.6218 / 2N/ANo
4421532D structure3-MPPIC23H25N5O3419.4855 / 22.7Yes
126282D structureCHEMBL62033C24H24N4O3416.4815 / 12.5Yes
127572D structureCHEMBL327168C24H30N6O2434.5447 / 13.2Yes
135742D structureCHEMBL91989C27H32F3N5O2515.5819 / 15.3No
136742D structure8-OH-DpatC16H25NO247.3822 / 14.1Yes
139752D structureCHEMBL57364C21H28ClN3O2389.9244 / 03.5Yes
149742D structureCHEMBL434591C25H25N3O3S447.5535 / 14.2Yes
152862D structureCHEMBL1256344C34H40N4O6600.7168 / 14.2No
153392D structureCHEMBL291305C26H32N2O4436.5525 / 03.5Yes
159262D structureCHEMBL40819C25H24N4O5S492.557 / 14.0Yes
162752D structureCHEMBL88181C23H31N3O2S413.585 / 03.9Yes
166912D structureCHEMBL303988C25H31N3O4437.546 / 13.4Yes
169222D structureCHEMBL53675C21H26F4N4O3458.4589 / 13.2Yes
171742D structureCHEMBL56150C21H27Cl2N3O2424.3664 / 04.1Yes
178872D structureBmy-7378C22H31N3O3385.5085 / 02.8Yes
187542D structureCHEMBL59033C19H25ClN2O3364.874 / 13.1Yes
191422D structureCHEMBL1255003C25H29NO3391.5114 / 15.3No
4424202D structureCHEMBL3415013C25H32N4O2420.5574 / 23.5Yes
196082D structureCHEMBL327116C15H19N3O2S305.3964 / 22.1Yes
215402D structureCHEMBL40780C26H24N4O3S472.5636 / 13.9Yes
215962D structureCHEMBL14213C26H28N4O3S476.5956 / 04.1Yes
216922D structureCHEMBL89916C26H39N5O2453.6316 / 14.4Yes
227692D structureCHEMBL294705C23H32N4O4428.5336 / 03.5Yes
229622D structureCHEMBL382972C26H31NO5437.5366 / 14.9Yes
230132D structureCHEMBL417890C25H25N3O4431.4925 / 13.5Yes
4426082D structureCHEMBL3342872C23H31N3O5S2493.6379 / 02.7Yes
250492D structureCHEMBL42231C27H31NO3417.5494 / 15.5No
265482D structureRauwolscineC21H26N2O3354.454 / 22.9Yes
266202D structureYohimbineC21H26N2O3354.454 / 22.9Yes
282202D structureCHEMBL209043C17H15ClN2O298.772 / 03.8Yes
286512D structureCHEMBL313775C25H32F3N7O2519.57310 / 24.1No
293692D structureCHEMBL2153559C20H25NO6375.4217 / 12.9Yes
4428232D structureCHEMBL3415017C23H27BrN4O2471.3994 / 24.3Yes
300382D structureHistaprodifenC20H23N3305.4252 / 23.5Yes
301192D structureCHEMBL495289C25H27NO3389.4954 / 14.0Yes
302542D structureCHEMBL111372C14H17N3O3S307.3685 / 31.4Yes
4428432D structureCHEMBL3342856C19H29N3O3347.4596 / 11.4Yes
303432D structureCHEMBL293539C21H27ClFN3O2407.9145 / 03.6Yes
4428712D structureCHEMBL3342855C19H28N2O5S396.5027 / 01.2Yes
320342D structureCHEMBL88160C26H34F3N7O2533.610 / 14.3No
4429972D structureCHEMBL3342866C25H33N3O5S487.6158 / 02.7Yes
341162D structureCHEMBL417954C19H21F5N4O3448.39410 / 12.7Yes
342152D structureCHEMBL58384C21H27ClIN3O2515.824 / 04.1No
4430252D structureCHEMBL3342873C20H31N3O5S425.5448 / 01.1Yes
4430632D structureCHEMBL385371C26H30ClNO4455.9795 / 2N/AN/A
358002D structureCHEMBL299454C21H30ClN3O375.9413 / 04.1Yes
361632D structureCHEMBL433348C23H30N4O2394.5196 / 13.8Yes
371022D structureCHEMBL2115086C21H23N3O3S397.4935 / 12.8Yes
371042D structureCHEMBL291839C21H23N3O3S397.4935 / 12.8Yes
371112D structureCHEMBL55460C20H27Cl2N3O2412.3554 / 14.2Yes
378352D structureCHEMBL327527C27H30FN7O487.5835 / 13.2Yes
392162D structureCHEMBL92901C22H31N5O2397.5236 / 23.3Yes
393012D structureCHEMBL61598C25H28N4O4448.5235 / 22.0Yes
396372D structureCHEMBL207950C23H20N2O3372.4244 / 04.3Yes
405662D structureCHEMBL56375C20H26F4N4O5478.44511 / 31.3No
409802D structureCHEMBL145384C26H34ClN5O3500.047 / 14.6No
411072D structureCHEMBL1946781C28H29NO6475.5417 / 3N/AN/A
416962D structureL-765314C27H34N6O5522.6069 / 23.1No
439232D structureCHEMBL388884C23H26BrN5O4516.3968 / 14.4No
441512D structureCHEMBL1259158C25H33N3OS423.6194 / 14.2Yes
447512D structureCHEMBL60510C25H29N3O3419.5254 / 13.5Yes
450532D structureCHEMBL503007C32H36N4O6572.6628 / 13.4No
477822D structureCHEMBL1630940C20H25F3N2O5S462.48410 / 23.5Yes
478322D structureCHEMBL62109C24H26ClN3O4455.9395 / 13.4Yes
479552D structureCHEMBL2153551C19H23NO6361.3947 / 22.5Yes
480232D structureCHEMBL2153555C19H22ClNO5379.8376 / 13.5Yes
488582D structureCHEMBL293674C17H16N2O2280.3273 / 02.8Yes
489172D structureCHEMBL57797C20H25Cl2N3O3426.3384 / 13.4Yes
492872D structureCHEMBL60699C29H38N4O3490.6486 / 02.9Yes
495982D structureCHEMBL330579C23H30F3N5O2465.5219 / 14.3Yes
499442D structureCHEMBL302192C25H33N3O3423.5576 / 13.7Yes
501742D structureCHEMBL121943C22H22F3N5O3461.44510 / 13.5Yes
507062D structureCHEMBL66432C16H14N2O2266.33 / 12.6Yes
533812D structureCHEMBL299691C21H28FN3O2373.4725 / 02.9Yes
536482D structureCHEMBL327351C22H31N5O3413.5227 / 22.8Yes
543792D structureCHEMBL301650C20H22F6N4O3480.41111 / 13.2No

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