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Ligand

NameL-765314
Molecular formulaC27H34N6O5
IUPAC namebenzyl (2S)-4-(4-amino-6,7-dimethoxyquinazolin-2-yl)-2-(tert-butylcarbamoyl)piperazine-1-carboxylate
Molecular weight522.606
Hydrogen bond acceptor9
Hydrogen bond donor2
XlogP3.1
SynonymsCHEMBL19476
CGWOIDCAGBKOQL-FQEVSTJZSA-N
NCGC00094440-01
189349-50-6
NCGC00015604-01
[ Show all ]
Inchi KeyCGWOIDCAGBKOQL-FQEVSTJZSA-N
Inchi IDInChI=1S/C27H34N6O5/c1-27(2,3)31-24(34)20-15-32(11-12-33(20)26(35)38-16-17-9-7-6-8-10-17)25-29-19-14-22(37-5)21(36-4)13-18(19)23(28)30-25/h6-10,13-14,20H,11-12,15-16H2,1-5H3,(H,31,34)(H2,28,29,30)/t20-/m0/s1
PubChem CID6603904
ChEMBLCHEMBL19476
IUPHAR506
BindingDB50063907
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand is heavier than 500 daltons.

Known GPCRs

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Total entries: 8
Page:  / 1 

GLASS IDNameUniProtGeneSpeciesLength
41694Alpha-1A adrenergic receptorP35348ADRA1AHomo sapiens (Human)466
41698Alpha-1A adrenergic receptorP43140Adra1aRattus norvegicus (Rat)466
41690Alpha-1B adrenergic receptorP35368ADRA1BHomo sapiens (Human)520
41695Alpha-1B adrenergic receptorP15823Adra1bRattus norvegicus (Rat)515
41696Alpha-1D adrenergic receptorP23944Adra1dRattus norvegicus (Rat)561
41697Alpha-1D adrenergic receptorP25100ADRA1DHomo sapiens (Human)572
41691Muscarinic acetylcholine receptor M1P08482Chrm1Rattus norvegicus (Rat)460
41692Thyrotropin receptorP16473TSHRHomo sapiens (Human)764

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