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Ligand

NameCHEMBL46395
Molecular formulaC22H30F3NO4
IUPAC name7-[(2S)-2-[(3R)-3-hydroxy-4-[3-(trifluoromethyl)phenyl]butyl]-5-oxopyrrolidin-1-yl]heptanoic acid
Molecular weight429.48
Hydrogen bond acceptor7
Hydrogen bond donor2
XlogP3.9
Synonyms7-((S)-2-((R)-3-hydroxy-4-(3-(trifluoromethyl)phenyl)butyl)-5-oxopyrrolidin-1-yl)heptanoic acid
7-{(S)-2-[(R)-3-Hydroxy-4-(3-trifluoromethyl-phenyl)-butyl]-5-oxo-pyrrolidin-1-yl}-heptanoic acid
BDBM50142488
SCHEMBL6161931
Inchi KeyBGIIQHLOAQSIFC-RBUKOAKNSA-N
Inchi IDInChI=1S/C22H30F3NO4/c23-22(24,25)17-7-5-6-16(14-17)15-19(27)11-9-18-10-12-20(28)26(18)13-4-2-1-3-8-21(29)30/h5-7,14,18-19,27H,1-4,8-13,15H2,(H,29,30)/t18-,19+/m0/s1
PubChem CID10113454
ChEMBLCHEMBL46395
IUPHARN/A
BindingDB50142488
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

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Total entries: 5
Page:  / 1 

GLASS IDNameUniProtGeneSpeciesLength
23033Prostaglandin E2 receptor EP2 subtypeP43116PTGER2Homo sapiens (Human)358
23035Prostaglandin E2 receptor EP2 subtypeQ62928Ptger2Rattus norvegicus (Rat)357
23034Prostaglandin E2 receptor EP3 subtypeP43115PTGER3Homo sapiens (Human)390
23032Prostaglandin E2 receptor EP4 subtypeP43114Ptger4Rattus norvegicus (Rat)488
23036Prostaglandin E2 receptor EP4 subtypeP35408PTGER4Homo sapiens (Human)488

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