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Ligand

NameCHEMBL2440659
Molecular formulaC15H11FN4O2S
IUPAC name3-fluoro-N-(4-methyl-1,3-thiazol-2-yl)-5-pyrimidin-5-yloxybenzamide
Molecular weight330.337
Hydrogen bond acceptor7
Hydrogen bond donor1
XlogP2.4
SynonymsAXVLPJHYYFHCHK-UHFFFAOYSA-N
SCHEMBL1487938
MolPort-039-338-054
BDBM50442525
ZINC68251494
[ Show all ]
Inchi KeyAXVLPJHYYFHCHK-UHFFFAOYSA-N
Inchi IDInChI=1S/C15H11FN4O2S/c1-9-7-23-15(19-9)20-14(21)10-2-11(16)4-12(3-10)22-13-5-17-8-18-6-13/h2-8H,1H3,(H,19,20,21)
PubChem CID50990953
ChEMBLCHEMBL2440659
IUPHARN/A
BindingDB50442525
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

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Total entries: 37
Page:  / 2 

GLASS IDNameUniProtGeneSpeciesLength
171565-hydroxytryptamine receptor 1AP08908HTR1AHomo sapiens (Human)422
171535-hydroxytryptamine receptor 2BP41595HTR2BHomo sapiens (Human)481
17143Adenosine receptor A1P30542ADORA1Homo sapiens (Human)326
17140Adenosine receptor A2aP29274ADORA2AHomo sapiens (Human)412
442337Adenosine receptor A3P0DMS8ADORA3Homo sapiens (Human)318
17149Alpha-1A adrenergic receptorP43140Adra1aRattus norvegicus (Rat)466
17130Alpha-1B adrenergic receptorP15823Adra1bRattus norvegicus (Rat)515
17142Alpha-1D adrenergic receptorP25100ADRA1DHomo sapiens (Human)572
17124Alpha-2A adrenergic receptorP08913ADRA2AHomo sapiens (Human)450
17135B1 bradykinin receptorP46663BDKRB1Homo sapiens (Human)353
17155B2 bradykinin receptorP30411BDKRB2Homo sapiens (Human)391
17139Beta-1 adrenergic receptorP08588ADRB1Homo sapiens (Human)477
17128Beta-2 adrenergic receptorP07550ADRB2Homo sapiens (Human)413
17137Cannabinoid receptor 1P21554CNR1Homo sapiens (Human)472
17126Cysteinyl leukotriene receptor 1Q9Y271CYSLTR1Homo sapiens (Human)337
17134D(1A) dopamine receptorP21728DRD1Homo sapiens (Human)446
17154D(2) dopamine receptorP14416DRD2Homo sapiens (Human)443
17150D(3) dopamine receptorP35462DRD3Homo sapiens (Human)400
17132Delta-type opioid receptorP41143OPRD1Homo sapiens (Human)372
17152Endothelin receptor type BP24530EDNRBHomo sapiens (Human)442

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