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Ligand

Name(+)-fluprostenol
Molecular formulaC23H29F3O6
IUPAC name7-[3,5-dihydroxy-2-[3-hydroxy-4-[3-(trifluoromethyl)phenoxy]but-1-enyl]cyclopentyl]hept-5-enoic acid
Molecular weight458.474
Hydrogen bond acceptor9
Hydrogen bond donor4
XlogP2.9
Synonyms(+/-)16-(m-Trifluoromethylphenoxy)-tetranor-prostaglandin F2alpha
15(S)-Fluprostenol
2-?methyl-?1S,?2,?3R,?7S,?8S,?8aR-?hexahydro-?3,?7-?dimethyl-?8-?[2-?[(2R,?4R)-?tetrahydro-?4-?hydroxy-?6-?oxo-?2H-?pyran-?2-?yl]ethyl]-?1-?naphthalenyl ester,? butanoic acid
54276-17-4
54276-24-3
[ Show all ]
Inchi KeyWWSWYXNVCBLWNZ-UHFFFAOYSA-N
Inchi IDInChI=1S/C23H29F3O6/c24-23(25,26)15-6-5-7-17(12-15)32-14-16(27)10-11-19-18(20(28)13-21(19)29)8-3-1-2-4-9-22(30)31/h1,3,5-7,10-12,16,18-21,27-29H,2,4,8-9,13-14H2,(H,30,31)
PubChem CID3391
ChEMBLN/A
IUPHARN/A
BindingDB85173
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

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Total entries: 10
Page:  / 1 

GLASS IDNameUniProtGeneSpeciesLength
384211Prostacyclin receptorP43119PTGIRHomo sapiens (Human)386
384214Prostaglandin D2 receptorQ13258PTGDRHomo sapiens (Human)359
384218Prostaglandin E2 receptor EP1 subtypeP34995PTGER1Homo sapiens (Human)402
384212Prostaglandin E2 receptor EP2 subtypeP43116PTGER2Homo sapiens (Human)358
384213Prostaglandin E2 receptor EP3 subtypeP34979PTGER3Bos taurus (Bovine)417
384219Prostaglandin E2 receptor EP3 subtypeP43115PTGER3Homo sapiens (Human)390
384220Prostaglandin E2 receptor EP4 subtypeP35408PTGER4Homo sapiens (Human)488
384215Prostaglandin F2-alpha receptorP37289PTGFRBos taurus (Bovine)362
384216Prostaglandin F2-alpha receptorP43088PTGFRHomo sapiens (Human)359
384217Prostaglandin F2-alpha receptorP43117PtgfrMus musculus (Mouse)366

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