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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL487476
Molecular formula	C30H29Cl2N3O5
IUPAC name	(2R)-3-[[4-[[4-(cyclohexen-1-yl)-N-[(3,5-dichlorophenyl)carbamoyl]anilino]methyl]benzoyl]amino]-2-hydroxypropanoic acid
Molecular weight	582.478
Hydrogen bond acceptor	5
Hydrogen bond donor	4
XlogP	5.4
Synonyms	NNC-25-0926 (2r)-N-[4-({4-(1-cyclohexen-1-yl)[(3,5-dichloroanilino)carbonyl]anilino}methyl)benzoyl]-2-hydroxy-beta-alanine SCHEMBL2651188 BDBM50244455
Inchi Key	XNSJRSAITGCUKS-HHHXNRCGSA-N
Inchi ID	InChI=1S/C30H29Cl2N3O5/c31-23-14-24(32)16-25(15-23)34-30(40)35(26-12-10-21(11-13-26)20-4-2-1-3-5-20)18-19-6-8-22(9-7-19)28(37)33-17-27(36)29(38)39/h4,6-16,27,36H,1-3,5,17-18H2,(H,33,37)(H,34,40)(H,38,39)/t27-/m1/s1
PubChem CID	10032265
ChEMBL	CHEMBL487476
IUPHAR	N/A
BindingDB	50244455
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
396620	Gastric inhibitory polypeptide receptor	P48546	GIPR	Homo sapiens (Human)	466
396622	Gastric inhibitory polypeptide receptor	P43219	Gipr	Rattus norvegicus (Rat)	455
396619	Glucagon receptor	P47871	GCGR	Homo sapiens (Human)	477
396621	Glucagon receptor	P30082	Gcgr	Rattus norvegicus (Rat)	485
396618	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463

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