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Ligand

Nameparoxetine
Molecular formulaC19H20FNO3
IUPAC name(3S,4R)-3-(1,3-benzodioxol-5-yloxymethyl)-4-(4-fluorophenyl)piperidine
Molecular weight329.371
Hydrogen bond acceptor5
Hydrogen bond donor1
XlogP3.5
Synonyms61869-08-7
Paxil
Paxil CR
Seroxat
Paxetil
[ Show all ]
Inchi KeyAHOUBRCZNHFOSL-YOEHRIQHSA-N
Inchi IDInChI=1S/C19H20FNO3/c20-15-3-1-13(2-4-15)17-7-8-21-10-14(17)11-22-16-5-6-18-19(9-16)24-12-23-18/h1-6,9,14,17,21H,7-8,10-12H2/t14-,17-/m0/s1
PubChem CID43815
ChEMBLCHEMBL490
IUPHARN/A
BindingDB22416
DrugBankDB00715

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

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Total entries: 27
Page:  / 2 

GLASS IDNameUniProtGeneSpeciesLength
57655-hydroxytryptamine receptor 1AP08908HTR1AHomo sapiens (Human)422
57665-hydroxytryptamine receptor 1AP19327Htr1aRattus norvegicus (Rat)422
57675-hydroxytryptamine receptor 1BP28564Htr1bRattus norvegicus (Rat)386
57705-hydroxytryptamine receptor 2AP14842Htr2aRattus norvegicus (Rat)471
57755-hydroxytryptamine receptor 2AP28223HTR2AHomo sapiens (Human)471
57685-hydroxytryptamine receptor 2BP41595HTR2BHomo sapiens (Human)481
57625-hydroxytryptamine receptor 2CP28335HTR2CHomo sapiens (Human)458
57715-hydroxytryptamine receptor 2CP08909Htr2cRattus norvegicus (Rat)460
5776Alpha-1A adrenergic receptorP43140Adra1aRattus norvegicus (Rat)466
555504Alpha-1A adrenergic receptorP35348ADRA1AHomo sapiens (Human)466
5773Alpha-2A adrenergic receptorP08913ADRA2AHomo sapiens (Human)450
5772Alpha-2C adrenergic receptorP22086Adra2cRattus norvegicus (Rat)458
459275Beta-2 adrenergic receptorP10608Adrb2Rattus norvegicus (Rat)418
5758D(1A) dopamine receptorP18901Drd1Rattus norvegicus (Rat)446
5774D(1A) dopamine receptorP21728DRD1Homo sapiens (Human)446
555505D(2) dopamine receptorP14416DRD2Homo sapiens (Human)443
555506D(2) dopamine receptorP61169Drd2Rattus norvegicus (Rat)444
5754Histamine H1 receptorP35367HRH1Homo sapiens (Human)487
5761Histamine H1 receptorP31390Hrh1Rattus norvegicus (Rat)486
5764Histamine H1 receptorP31389HRH1Cavia porcellus (Guinea pig)488

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