Home Research COVID-19 Services Publications People Teaching Job Opening News Forum Lab Only
Online Services

I-TASSER QUARK LOMETS COACH COFACTOR MetaGO MUSTER CEthreader SEGMER FG-MD ModRefiner REMO DEMO SPRING COTH BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign GPCR-I-TASSER MAGELLAN BindProf BindProfX SSIPe ResQ IonCom STRUM DAMpred

TM-score TM-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE WDL-RF ATPbind DockRMSD DeepMSA FASPR

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13

You can:

Ligand

NameCHEMBL2426616
Molecular formulaC14H14N2O2S
IUPAC name5-methyl-2-(phenoxymethyl)-6,7-dihydro-[1,3]thiazolo[5,4-c]pyridin-4-one
Molecular weight274.338
Hydrogen bond acceptor4
Hydrogen bond donor0
XlogP2.3
SynonymsSCHEMBL2011730
BDBM50440185
ZINC72315235
5-Methyl-2-(phenoxymethyl)-6,7-dihydrothiazolo[5,4-c]pyridine-4(5H)-one
Inchi KeyAOOAPFRKSGWOER-UHFFFAOYSA-N
Inchi IDInChI=1S/C14H14N2O2S/c1-16-8-7-11-13(14(16)17)19-12(15-11)9-18-10-5-3-2-4-6-10/h2-6H,7-9H2,1H3
PubChem CID67246999
ChEMBLCHEMBL2426616
IUPHARN/A
BindingDB50440185
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Total entries: 9
Page:  / 1 

GLASS IDNameUniProtGeneSpeciesLength
10406Metabotropic glutamate receptor 1Q13255GRM1Homo sapiens (Human)1194
10404Metabotropic glutamate receptor 2Q14416GRM2Homo sapiens (Human)872
10402Metabotropic glutamate receptor 3Q14832GRM3Homo sapiens (Human)879
10405Metabotropic glutamate receptor 4Q14833GRM4Homo sapiens (Human)912
10398Metabotropic glutamate receptor 5P31424Grm5Rattus norvegicus (Rat)1203
10401Metabotropic glutamate receptor 5P41594GRM5Homo sapiens (Human)1212
10399Metabotropic glutamate receptor 6P35349Grm6Rattus norvegicus (Rat)871
10403Metabotropic glutamate receptor 7Q14831GRM7Homo sapiens (Human)915
10400Metabotropic glutamate receptor 8O00222GRM8Homo sapiens (Human)908

yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218