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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL40123
Molecular formula	C19H21NO4
IUPAC name	(2S,4S)-2-amino-4-(2,2-diphenylethyl)pentanedioic acid
Molecular weight	327.38
Hydrogen bond acceptor	5
Hydrogen bond donor	3
XlogP	0.3
Synonyms	(2S,4S)-2-Amino-4-(2,2-diphenyl-ethyl)-pentanedioic acid ZINC13797034 (2S,4S)-2-amino-4-(2,2-diphenylethyl)pentanedioic Acid BDBM50069111 SCHEMBL187449 2-Amino-4-(2,2-diphenyl-ethyl)-pentanedioic acid [ Show all ]
Inchi Key	LSXSDBGWRLZZIR-RDJZCZTQSA-N
Inchi ID	InChI=1S/C19H21NO4/c20-17(19(23)24)12-15(18(21)22)11-16(13-7-3-1-4-8-13)14-9-5-2-6-10-14/h1-10,15-17H,11-12,20H2,(H,21,22)(H,23,24)/t15-,17-/m0/s1
PubChem CID	10359073
ChEMBL	CHEMBL40123
IUPHAR	N/A
BindingDB	50069111
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
195665	Metabotropic glutamate receptor 1	Q13255	GRM1	Homo sapiens (Human)	1194
195661	Metabotropic glutamate receptor 2	Q14416	GRM2	Homo sapiens (Human)	872
195660	Metabotropic glutamate receptor 3	Q14832	GRM3	Homo sapiens (Human)	879
195664	Metabotropic glutamate receptor 4	Q14833	GRM4	Homo sapiens (Human)	912
195666	Metabotropic glutamate receptor 5	P41594	GRM5	Homo sapiens (Human)	1212
195662	Metabotropic glutamate receptor 7	Q14831	GRM7	Homo sapiens (Human)	915
195663	Metabotropic glutamate receptor 8	O00222	GRM8	Homo sapiens (Human)	908

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