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Ligand

NameBCTC
Molecular formulaC20H25ClN4O
IUPAC nameN-(4-tert-butylphenyl)-4-(3-chloropyridin-2-yl)piperazine-1-carboxamide
Molecular weight372.897
Hydrogen bond acceptor3
Hydrogen bond donor1
XlogP4.3
Synonyms393514-24-4
N-(4-tert-butylphenyl)-4-(3-chloropyridin-2-yl)piperazine-1-carboxamide
CHEMBL441472
4-(3-Chloro-2-pyridinyl)-N-[4-(1,1-dimethylethyl)phenyl]-1-piperazinecarboxamide, BCTC
D0P7VQ
[ Show all ]
Inchi KeyROGUAPYLUCHQGK-UHFFFAOYSA-N
Inchi IDInChI=1S/C20H25ClN4O/c1-20(2,3)15-6-8-16(9-7-15)23-19(26)25-13-11-24(12-14-25)18-17(21)5-4-10-22-18/h4-10H,11-14H2,1-3H3,(H,23,26)
PubChem CID9929425
ChEMBLN/A
IUPHARN/A
BindingDB50133817
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

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Total entries: 25
Page:  / 2 

GLASS IDNameUniProtGeneSpeciesLength
301161Alpha-1A adrenergic receptorP43140Adra1aRattus norvegicus (Rat)466
301171Alpha-2C adrenergic receptorP22086Adra2cRattus norvegicus (Rat)458
556664B2 bradykinin receptorP25023Bdkrb2Rattus norvegicus (Rat)396
461793Beta-2 adrenergic receptorP10608Adrb2Rattus norvegicus (Rat)418
301154Cysteinyl leukotriene receptor 1Q924T8Cysltr1Rattus norvegicus (Rat)339
556662D(1A) dopamine receptorP18901Drd1Rattus norvegicus (Rat)446
301156Endothelin receptor type BP21451EdnrbRattus norvegicus (Rat)442
301159Endothelin-1 receptorP26684EdnraRattus norvegicus (Rat)426
556661Gamma-aminobutyric acid type B receptor subunit 1Q9Z0U4Gabbr1Rattus norvegicus (Rat)991
301169Gastrin/cholecystokinin type B receptorP30553CckbrRattus norvegicus (Rat)452
301164Histamine H1 receptorP31390Hrh1Rattus norvegicus (Rat)486
301172Histamine H2 receptorP25102Hrh2Rattus norvegicus (Rat)358
301157Leukotriene B4 receptor 1Q9R0Q2Ltb4rRattus norvegicus (Rat)351
301167Melatonin receptor type 1AP49218Mtnr1aRattus norvegicus (Rat)156
301168Mu-type opioid receptorP33535Oprm1Rattus norvegicus (Rat)398
301170Muscarinic acetylcholine receptor M1P08482Chrm1Rattus norvegicus (Rat)460
301165Muscarinic acetylcholine receptor M2P10980Chrm2Rattus norvegicus (Rat)466
461794Neuromedin-K receptorP47937Tacr3Mus musculus (Mouse)452
301155Oxytocin receptorP70536OxtrRattus norvegicus (Rat)388
301163Platelet-activating factor receptorP46002PtafrRattus norvegicus (Rat)341

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