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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	N6-Cyclopentyladenosine
Molecular formula	C15H21N5O4
IUPAC name	(2R,3R,4S,5R)-2-[6-(cyclopentylamino)purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol
Molecular weight	335.364
Hydrogen bond acceptor	8
Hydrogen bond donor	4
XlogP	0.9
Synonyms	MolPort-023-276-193 N6-CyclopentylAdo SMR000058639 41552-82-3 BDBM25400 HMS2232M15 n-cyclopentyladenosine NCGC00023909-06 UNII-7LG47VG1ID (2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol AC-27402 cid_657378 LS-15119 MLS001077332 N6-cyclopentyladenosine (CPA) PDSP2_001053 AJ-47612 D03RFA N(6)-Cyclopentyladenosine NCGC00023909-04 SQMWSBKSHWARHU-SDBHATRESA-N 5720AB J-523544 n6-cyclopentyl-adenosine Opera_ID_1056 ZINC3995996 (2R,3R,4S,5R)-2-[6-(cyclopentylamino)purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol AC1LCWG1 CTK1D5898 MFCD00036845 MLS002153196 N6-Cyclopentyladenosine, solid SCHEMBL120481 3GU AKOS016009596 GTPL380 n-cyclopentyl-adenosine NCGC00023909-05 ST24026157 (2R,3R,4S,5R)-2-(6-(Cyclopentylamino)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol 7LG47VG1ID CHEMBL68738 KB-206470 PDSP1_001069 Adenosine, N-cyclopentyl- Cyclopentyladenosine MLS000028368 [ Show all ]
Inchi Key	SQMWSBKSHWARHU-SDBHATRESA-N
Inchi ID	InChI=1S/C15H21N5O4/c21-5-9-11(22)12(23)15(24-9)20-7-18-10-13(16-6-17-14(10)20)19-8-3-1-2-4-8/h6-9,11-12,15,21-23H,1-5H2,(H,16,17,19)/t9-,11-,12-,15-/m1/s1
PubChem CID	657378
ChEMBL	CHEMBL68738
IUPHAR	380
BindingDB	25400
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
320764	Adenosine receptor A1	P25099	Adora1	Rattus norvegicus (Rat)	326
320766	Adenosine receptor A1	P30542	ADORA1	Homo sapiens (Human)	326
320767	Adenosine receptor A1	P47745	ADORA1	Cavia porcellus (Guinea pig)	326
320771	Adenosine receptor A1	P28190	ADORA1	Bos taurus (Bovine)	326
320778	Adenosine receptor A1	P49892	ADORA1	Gallus gallus (Chicken)	324
320779	Adenosine receptor A1	P34970	ADORA1	Oryctolagus cuniculus (Rabbit)	328
320765	Adenosine receptor A2a	P29274	ADORA2A	Homo sapiens (Human)	412
320770	Adenosine receptor A2a	P30543	Adora2a	Rattus norvegicus (Rat)	410
320773	Adenosine receptor A2b	P29275	ADORA2B	Homo sapiens (Human)	332
320768	Adenosine receptor A3	P28647	Adora3	Rattus norvegicus (Rat)	320
320769	Adenosine receptor A3	P0DMS8	ADORA3	Homo sapiens (Human)	318
320775	Adenosine receptor A3	O02667	ADORA3	Oryctolagus cuniculus (Rabbit)	319
320774	Alpha-1A adrenergic receptor	P35348	ADRA1A	Homo sapiens (Human)	466
320777	Relaxin receptor 1	Q9HBX9	RXFP1	Homo sapiens (Human)	757
320772	Relaxin receptor 2	Q8WXD0	RXFP2	Homo sapiens (Human)	754
320776	Vasopressin V1b receptor	P47901	AVPR1B	Homo sapiens (Human)	424

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