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BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13

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GPCR

NameD(2) dopamine receptor
SpeciesBos taurus (Bovine)
GeneDRD2
SynonymDopamine D2 receptor
DiseaseN/A for non-human GPCRs
Length444
Amino acid sequenceMDPLNLSWYDDDPESRNWSRPFNGSEGKADRPPYNYYAMLLTLLIFVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPMLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRANLKAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKTVNPKIAKIFEIQSMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC
UniProtP20288
Protein Data BankN/A
GPCR-HGmod modelN/A
3D structure modelNo available structures or models
BioLiPN/A
Therapeutic Target DatabaseN/A
ChEMBLCHEMBL3998
IUPHARN/A
DrugBankN/A

Known ligands

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Total entries: 487
Page:  / 5 

GLASS IDMoleculeFormulaMolecular weightH-bond acceptor / donorXlogPLipinski's druglikeness
422D structureCHEMBL171316C23H28N4S392.5655 / 14.9Yes
42242D structureCHEMBL25984C15H23NO233.3552 / 03.8Yes
5554992D structureMoperoneC22H26FNO2355.4534 / 13.0Yes
49772D structureCHEMBL50188C25H36N2O4428.5735 / 04.2Yes
55362D structureCHEMBL538235C15H22ClNO2283.7963 / 23.5Yes
55432D structureCHEMBL50722C25H36N2O5444.5726 / 04.3Yes
55492D structureCHEMBL57470C14H15NO3245.2784 / 41.8Yes
59162D structureCHEMBL50722C27H38N2O9534.60610 / 2N/ANo
72872D structureCHEMBL367343C18H24N2O2300.4024 / 22.7Yes
73112D structureCHEMBL289557C16H24ClNO281.8242 / 14.7Yes
91472D structureCHEMBL144114C16H25N231.3831 / 04.1Yes
95982D structureCHEMBL80437C18H25N3283.4192 / 13.9Yes
97662D structureCHEMBL172205C17H25NO259.3932 / 13.9Yes
105282D structureCHEMBL341825C16H25N231.3831 / 04.1Yes
112172D structureCHEMBL173042C22H30N2S354.5562 / 15.7No
5555262D structurepropranololC16H21NO2259.3493 / 23.0Yes
118102D structureCHEMBL54266C23H32N2O4S432.5796 / 14.3Yes
124322D structureCHEMBL40949C21H26ClNO3375.8934 / 35.1No
129332D structureCHEMBL95208C13H24N4O3284.364 / 4-0.8Yes
129342D structureCHEMBL420258C13H24N4O3284.364 / 4-0.8Yes
136202D structureADTNC10H13NO2179.2193 / 31.4Yes
136472D structure8-OH-DpatC16H25NO247.3822 / 14.1Yes
5555512D structurePipamperoneC21H30FN3O2375.4885 / 12.0Yes
179282D structureCHEMBL492042C19H20BrClN4419.7513 / 14.7Yes
5555602D structureimipramineC19H24N2280.4152 / 04.8Yes
202982D structureCHEMBL353848C19H24N2S312.4752 / 14.3Yes
206182D structureCHEMBL318924C14H24N2220.361 / 02.9Yes
207602D structureCHEMBL67355C17H19N5293.3744 / 11.7Yes
233772D structureCHEMBL127067C20H19BrClNO404.7322 / 04.8Yes
250862D structureCHEMBL544711C14H21N203.3291 / 03.4Yes
5555762D structureTeflutixolC23H26F4N2OS454.5288 / 14.6Yes
271152D structureCHEMBL301559C16H25NO247.3822 / 14.1Yes
299902D structureCHEMBL540272C15H22BrNO2328.253 / 23.6Yes
303372D structureCHEMBL311360C13H23N3221.3482 / 22.8Yes
303952D structureCHEMBL545203C13H18ClNO2255.7423 / 22.6Yes
325062D structureUNII-QQYOR9S587C18H29NO275.4362 / 04.8Yes
337972D structureCHEMBL555369C13H18BrNO2300.1963 / 32.7Yes
356272D structureCHEMBL522639C17H20N6308.3895 / 12.0Yes
359382D structureCHEMBL353678C21H27N3O337.4673 / 12.9Yes
5556232D structureUNII-F52O5YF6CAC24H25F4NOS451.5247 / 15.9No
409432D structureCHEMBL17231C15H22N2O2S294.4134 / 23.4Yes
410572D structureCHEMBL267853C17H18ClN5327.8164 / 03.2Yes
413112D structureCHEMBL60318C20H22FN3OS371.4745 / 03.9Yes
437892D structureCHEMBL483864C19H21ClN4340.8553 / 14.0Yes
444712D structureCHEMBL538745C13H19Cl2NO276.2012 / 2N/AN/A
444762D structureBDBM50060603C14H18N4O4S338.3825 / 1-1.2Yes
444772D structureCHEMBL607228C14H18N4O4S338.3825 / 1-1.2Yes
504192D structureCHEMBL44255C17H26FNO279.3993 / 14.4Yes
508752D structureCHEMBL520019C17H19ClN6342.8315 / 12.6Yes
546122D structureCHEMBL48925C25H34N2O4426.5575 / 14.6Yes
551192D structureCHEMBL299511C14H15NO2229.2793 / 32.2Yes
566722D structurecisaprideC23H29ClFN3O4465.957 / 23.4Yes
569562D structureCHEMBL544961C15H29N223.4041 / 04.9Yes
570472D structureCHEMBL77421C9H15N3165.242 / 20.9Yes
570552D structureCHEMBL543212C15H23BrN2O2S375.3254 / 3N/AN/A
573792D structureCHEMBL44419C12H16ClNO225.7162 / 13.0Yes
574052D structureCHEMBL298534C24H31FN2O3414.5215 / 14.7Yes
592612D structureCHEMBL64167C20H23N3OS353.4844 / 03.8Yes
5557162D structurespiperoneC23H26FN3O2395.4785 / 13.0Yes
623202D structureCHEMBL51888C22H30N2O4S418.5526 / 13.9Yes
625092D structureCHEMBL52438C19H25NO283.4152 / 05.1No
630572D structureCHEMBL418252C12H15Cl2NO260.1582 / 13.6Yes
630752D structureCHEMBL11592C26H38N2O4442.65 / 04.6Yes
632812D structureCHEMBL169702C23H31N3O365.5213 / 13.6Yes
646702D structurePD-168077C20H22N4O334.4234 / 13.0Yes
647042D structureCHEMBL332740C15H24N4O4324.3814 / 2-0.4Yes
647642D structureCHEMBL338119C16H23N3O2289.3793 / 22.5Yes
655892D structureCHEMBL510055C20H23ClN4O370.8814 / 14.0Yes
663382D structureCHEMBL483247C19H20Cl2N4375.2973 / 14.6Yes
666402D structureCHEMBL131186C18H29N3O2319.4493 / 22.4Yes
667292D structureCHEMBL171115C21H27N3O2353.4664 / 12.4Yes
672532D structureCHEMBL340541C20H18Cl3NO394.722 / 05.3No
673532D structureCHEMBL170356C17H20N2OS300.423 / 23.0Yes
678432D structureCHEMBL553258C15H23N217.3561 / 03.8Yes
683102D structureCHEMBL432676C10H12FNO2197.2094 / 31.1Yes
689332D structureCHEMBL268558C22H21ClN4376.8883 / 04.4Yes
689482D structureCHEMBL301060C28H40N2O8532.6349 / 2N/ANo
712682D structureBDBM50017525C17H23FN6330.4115 / 10.7Yes
727412D structureCHEMBL59741C20H20F3N3OS407.4557 / 14.5Yes
737402D structureFASDKYOPVNHBLU-UHFFFAOYSA-NC10H17N3S211.3274 / 21.9Yes
737442D structurepramipexoleC10H17N3S211.3274 / 21.9Yes
743502D structureCHEMBL176777C25H33N3O391.5593 / 14.2Yes
758092D structureCHEMBL131120C14H22N4246.3583 / 13.1Yes
5557622D structureBENPERIDOLC22H24FN3O2381.4514 / 13.7Yes
765852D structure(R)-zacoprideC15H20ClN3O2309.7944 / 21.7Yes
775542D structureCHEMBL99291C15H26N2O250.3862 / 12.1Yes
775582D structureCHEMBL95230C15H26N2O250.3862 / 12.1Yes
779222D structureCHEMBL177031C23H28ClN3O397.9473 / 14.0Yes
824572D structureCHEMBL485499C19H21BrN4385.3093 / 14.1Yes
836772D structureCHEMBL295196C16H24ClNO281.8242 / 14.7Yes
848782D structureCHEMBL352576C20H23F2N3O359.4215 / 12.7Yes
870652D structureQUINPIROLEC13H21N3219.3322 / 12.3Yes
880852D structureCHEMBL296395C22H24N2O4380.4445 / 12.9Yes
882732D structureCHEMBL50993C25H36N2O3412.5744 / 04.6Yes
885592D structureCHEMBL354362C22H24N2S348.5082 / 15.6No
885602D structureCHEMBL435263C22H24N2S348.5082 / 15.6No
899022D structureCHEMBL544038C13H19Cl2NO2292.23 / 3N/AN/A
900872D structure3-(3,4-Dimethylphenyl)-1-propyl-piperidine hydrochlorideC16H26ClN267.8411 / 1N/AN/A
929872D structureCHEMBL300735C24H34N2O4S446.6066 / 14.6Yes
5558182D structureD-Lysergic acid amideC16H18N3O+268.341 / 31.6Yes

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