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Ligand

Nameimipramine
Molecular formulaC19H24N2
IUPAC name3-(5,6-dihydrobenzo[b][1]benzazepin-11-yl)-N,N-dimethylpropan-1-amine
Molecular weight280.415
Hydrogen bond acceptor2
Hydrogen bond donor0
XlogP4.8
SynonymsMelipramine
Imidobenzyle
Antideprin
50-49-7
Berkomine
[ Show all ]
Inchi KeyBCGWQEUPMDMJNV-UHFFFAOYSA-N
Inchi IDInChI=1S/C19H24N2/c1-20(2)14-7-15-21-18-10-5-3-8-16(18)12-13-17-9-4-6-11-19(17)21/h3-6,8-11H,7,12-15H2,1-2H3
PubChem CID3696
ChEMBLCHEMBL11
IUPHAR357
BindingDB50010859
DrugBankDB00458

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

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Total entries: 40
Page:  / 3 

GLASS IDNameUniProtGeneSpeciesLength
201785-hydroxytryptamine receptor 1AP08908HTR1AHomo sapiens (Human)422
201965-hydroxytryptamine receptor 1AP19327Htr1aRattus norvegicus (Rat)422
201655-hydroxytryptamine receptor 2AP28223HTR2AHomo sapiens (Human)471
5555595-hydroxytryptamine receptor 2AP14842Htr2aRattus norvegicus (Rat)471
201695-hydroxytryptamine receptor 2CP28335HTR2CHomo sapiens (Human)458
201755-hydroxytryptamine receptor 2CP34968Htr2cMus musculus (Mouse)459
201895-hydroxytryptamine receptor 2CP08909Htr2cRattus norvegicus (Rat)460
201825-hydroxytryptamine receptor 6P50406HTR6Homo sapiens (Human)440
201835-hydroxytryptamine receptor 6P31388Htr6Rattus norvegicus (Rat)436
201985-hydroxytryptamine receptor 7P34969HTR7Homo sapiens (Human)479
5555615-hydroxytryptamine receptor 7P32305Htr7Rattus norvegicus (Rat)448
442462Adenosine receptor A3P0DMS8ADORA3Homo sapiens (Human)318
20172Alpha-1A adrenergic receptorP35348ADRA1AHomo sapiens (Human)466
20193Alpha-1A adrenergic receptorP43140Adra1aRattus norvegicus (Rat)466
20199Alpha-1B adrenergic receptorP35368ADRA1BHomo sapiens (Human)520
20200Alpha-1D adrenergic receptorP25100ADRA1DHomo sapiens (Human)572
20194Alpha-2A adrenergic receptorP08913ADRA2AHomo sapiens (Human)450
20170Alpha-2C adrenergic receptorP22086Adra2cRattus norvegicus (Rat)458
20171Beta-1 adrenergic receptorP18090Adrb1Rattus norvegicus (Rat)466
459393Beta-2 adrenergic receptorP07550ADRB2Homo sapiens (Human)413

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