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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	2-benzyl-6,7,8,9-tetrahydro-5H-pyrimido[4,5-d]azepine
Molecular formula	C15H17N3
IUPAC name	2-benzyl-6,7,8,9-tetrahydro-5H-pyrimido[4,5-d]azepine
Molecular weight	239.322
Hydrogen bond acceptor	3
Hydrogen bond donor	1
XlogP	2.1
Synonyms	CZWQBSKNHUVZLI-UHFFFAOYSA-N PNU-57378E PF-3246799 PNU-181731A D02YNH SCHEMBL1620274 2-benzyl-6,7,8,9-tetrahydro-5H-pyrimido[5,4-d]azepine PHA-181731A AKOS027383987 CHEMBL1770373 PNU-57378 1065110-62-4 NCGC00485021-01 ZINC68150324 5-HT 2 agonists, Pharmacia BDBM50342538 PHA-670080 [ Show all ]
Inchi Key	CZWQBSKNHUVZLI-UHFFFAOYSA-N
Inchi ID	InChI=1S/C15H17N3/c1-2-4-12(5-3-1)10-15-17-11-13-6-8-16-9-7-14(13)18-15/h1-5,11,16H,6-10H2
PubChem CID	25070582
ChEMBL	CHEMBL1770373
IUPHAR	N/A
BindingDB	50342538
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
54734	5-hydroxytryptamine receptor 2A	O46635	HTR2A	Canis lupus familiaris (Dog)	470
54736	5-hydroxytryptamine receptor 2A	P28223	HTR2A	Homo sapiens (Human)	471
54730	5-hydroxytryptamine receptor 2B	P41595	HTR2B	Homo sapiens (Human)	481
54731	5-hydroxytryptamine receptor 2C	P28335	HTR2C	Homo sapiens (Human)	458
54735	5-hydroxytryptamine receptor 2C	Q60F97	HTR2C	Canis lupus familiaris (Dog)	458
54732	5-hydroxytryptamine receptor 6	P50406	HTR6	Homo sapiens (Human)	440
54733	Muscarinic acetylcholine receptor M1	P11229	CHRM1	Homo sapiens (Human)	460
54738	Muscarinic acetylcholine receptor M3	P20309	CHRM3	Homo sapiens (Human)	590
54737	Muscarinic acetylcholine receptor M4	P08173	CHRM4	Homo sapiens (Human)	479
54729	Muscarinic acetylcholine receptor M5	P08912	CHRM5	Homo sapiens (Human)	532

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