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Ligand

NameVanoxerine
Molecular formulaC28H32F2N2O
IUPAC name1-[2-[bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazine
Molecular weight450.574
Hydrogen bond acceptor5
Hydrogen bond donor0
XlogP5.6
Synonyms1-(2-(Bis(p-fluorophenyl)methoxy)ethyl)-4-(3-phenylpropyl)piperazine
1-(2-BIS -[4-FLUOROPHENYL]- METHOXYETHYL)-4-(3-PHENYL- 2-PROPYL)PIPERAZINE
1-(2-bis-[4-FLUOROPHENYL]-METHOXYETHYL)-4-(3-PHENYL-2-PROPYL)PIPERAZINE
1-[2-[bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazine
1-{2-[bis(4-fluorophenyl)methoxy]ethyl}-4-(3-phenylpropyl)piperazine
[ Show all ]
Inchi KeyNAUWTFJOPJWYOT-UHFFFAOYSA-N
Inchi IDInChI=1S/C28H32F2N2O/c29-26-12-8-24(9-13-26)28(25-10-14-27(30)15-11-25)33-22-21-32-19-17-31(18-20-32)16-4-7-23-5-2-1-3-6-23/h1-3,5-6,8-15,28H,4,7,16-22H2
PubChem CID3455
ChEMBLCHEMBL281594
IUPHARN/A
BindingDB22165
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand has a partition coefficient log P greater than 5.

Known GPCRs

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Total entries: 21
Page:  / 2 

GLASS IDNameUniProtGeneSpeciesLength
2188105-hydroxytryptamine receptor 1AP19327Htr1aRattus norvegicus (Rat)422
2188135-hydroxytryptamine receptor 1AP08908HTR1AHomo sapiens (Human)422
5563405-hydroxytryptamine receptor 2AP14842Htr2aRattus norvegicus (Rat)471
2188125-hydroxytryptamine receptor 2CP08909Htr2cRattus norvegicus (Rat)460
461136Adenosine receptor A3P0DMS8ADORA3Homo sapiens (Human)318
218814Alpha-1A adrenergic receptorP43140Adra1aRattus norvegicus (Rat)466
218809Alpha-2C adrenergic receptorP22086Adra2cRattus norvegicus (Rat)458
218811Beta-1 adrenergic receptorP18090Adrb1Rattus norvegicus (Rat)466
218805D(1A) dopamine receptorP18901Drd1Rattus norvegicus (Rat)446
218815D(1A) dopamine receptorP21728DRD1Homo sapiens (Human)446
556339D(2) dopamine receptorP61169Drd2Rattus norvegicus (Rat)444
556342D(2) dopamine receptorP14416DRD2Homo sapiens (Human)443
556341D(3) dopamine receptorP35462DRD3Homo sapiens (Human)400
461135Delta-type opioid receptorP41143OPRD1Homo sapiens (Human)372
218801Histamine H1 receptorP31390Hrh1Rattus norvegicus (Rat)486
218808Histamine H2 receptorP47747HRH2Cavia porcellus (Guinea pig)359
218804Kappa-type opioid receptorP41145OPRK1Homo sapiens (Human)380
218803Mu-type opioid receptorP35372OPRM1Homo sapiens (Human)400
218807Muscarinic acetylcholine receptor M1P08482Chrm1Rattus norvegicus (Rat)460
218806Muscarinic acetylcholine receptor M2P10980Chrm2Rattus norvegicus (Rat)466

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