Zhang Lab

University of Michigan

Home Research COVID-19 Services Publications People Teaching Job Opening News Forum Lab Only

Online Services

●I-TASSER ●I-TASSER-MTD ●C-I-TASSER ●CR-I-TASSER ●QUARK ●C-QUARK ●LOMETS ●MUSTER ●CEthreader ●SEGMER ●DeepFold ●DeepFoldRNA ●FoldDesign ●COFACTOR ●COACH ●MetaGO ●TripletGO ●IonCom ●FG-MD ●ModRefiner ●REMO ●DEMO ●DEMO-EM ●DMFold ●SPRING ●COTH ●Threpp ●PEPPI ●BSpred ●ANGLOR ●EDock ●BSP-SLIM ●SAXSTER ●FUpred ●ThreaDom ●ThreaDomEx ●EvoDesign ●BindProf ●BindProfX ●SSIPe ●GPCR-I-TASSER ●MAGELLAN ●ResQ ●STRUM ●DAMpred

●TM-score ●TM-align ●US-align ●MM-align ●RNA-align ●NW-align ●LS-align ●EDTSurf ●MVP ●MVP-Fit ●SPICKER ●HAAD ●PSSpred ●3DRobot ●MR-REX ●I-TASSER-MR ●SVMSEQ ●NeBcon ●ResPRE ●TripletRes ●DeepPotential ●WDL-RF ●ATPbind ●DockRMSD ●DeepMSA ●FASPR ●EM-Refiner ●GPU-I-TASSER

●BioLiP ●E. coli ●GLASS ●GPCR-HGmod ●GPCR-RD ●GPCR-EXP ●Tara-3D ●TM-fold ●DECOYS ●POTENTIAL ●RW/RWplus ●EvoEF ●HPSF ●THE-DB ●ADDRESS ●Alpaca-Antibody ●CASP7 ●CASP8 ●CASP9 ●CASP10 ●CASP11 ●CASP12 ●CASP13 ●CASP14

GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	fenoldopam
Molecular formula	C16H16ClNO3
IUPAC name	9-chloro-5-(4-hydroxyphenyl)-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol
Molecular weight	305.758
Hydrogen bond acceptor	4
Hydrogen bond donor	4
XlogP	2.4
Synonyms	Corlopam DSSTox_GSID_43896 Fenoldopamum L000254 NCGC00015444-05 1H-3-Benzazepine-7,8-diol, 6-chloro-2,3,4,5-tetrahydro-1-(4-hydroxyphenyl)- SCHEMBL34250 9-chloranyl-5-(4-hydroxyphenyl)-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol;methanesulfonic acid SKF-82526J AB00698256_16 BDBM60917 Carlacor (TN) D07946 EN300-119508 GTPL939 MCULE-7876003953 NCGC00025246-02 SK-82526 9-chloro-5-(4-hydroxyphenyl)-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol;methanesulfonic acid Tox21_110152_1 AC1Q3LHG BRD-A50684349-001-01-5 CCG-204646 CHEMBL588 DB00800 Fenoldopam (INN) HY-B0735 NCGC00015444-03 (R)-6-Chloro-2,3,4,5-tetrahydro-1-(4-hydroxyphenyl)-1H-3-benzazepine-7,8-diol PDSP2_001645 67287-54-1 (hydrobromide) SKF 82526-J AB00698256-13 API0007253 C07693 Corlopam (TN) DSSTox_RID_80083 Fenoldopamum [Latin] Lopac0_000556 NCGC00015444-06 27F569 SK&F-82526 9-chloro-5-(4-hydroxyphenyl)-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol SMR000469190 AB2000493 Biomol-NT_000042 CAS-67227-56-9 D0R6BI Fenodopam mesylate HMS2090G16 MLS001401388 NCGC00025246-03 67227-56-9 SK-82526-J TVURRHSHRRELCG-UHFFFAOYSA-N AKOS015906543 BRD-A50684349-003-01-1 CHEBI:5002 cid_49659 DSSTox_CID_23896 Fenoldopam [INN:BAN] I745 NCGC00015444-04 SCHEMBL13287212 87900-90-1 SKF-82526 AB00698256-15 BC220528 Carlacor CS-2979 DTXSID0043896 FT-0641107 LS-27993 NCGC00015444-07 6-chloro-1-(4-hydroxyphenyl)-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol SK&F-82526J 9-chloro-5-(4-hydroxyphenyl)-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol;mesylic acid Tox21_110152 AC1L1FPQ BPBio1_001265 CC-28388 HMS3715H14 MolPort-006-167-637 PDSP1_001661 67227-57-0 (mesylate) SKF 82526 AB0013872 VA10891 AN-38412 C-20379 [ Show all ]
Inchi Key	TVURRHSHRRELCG-UHFFFAOYSA-N
Inchi ID	InChI=1S/C16H16ClNO3/c17-15-11-5-6-18-8-13(9-1-3-10(19)4-2-9)12(11)7-14(20)16(15)21/h1-4,7,13,18-21H,5-6,8H2
PubChem CID	3341
ChEMBL	CHEMBL588
IUPHAR	939
BindingDB	60917
DrugBank	DB00800
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
328668	Adenosine receptor A2b	P29276	Adora2b	Rattus norvegicus (Rat)	332
328683	Alpha-1A adrenergic receptor	P35348	ADRA1A	Homo sapiens (Human)	466
328679	Alpha-1B adrenergic receptor	P35368	ADRA1B	Homo sapiens (Human)	520
328672	Alpha-1D adrenergic receptor	P25100	ADRA1D	Homo sapiens (Human)	572
328673	Alpha-2A adrenergic receptor	P08913	ADRA2A	Homo sapiens (Human)	450
328678	Alpha-2B adrenergic receptor	P18089	ADRA2B	Homo sapiens (Human)	450
328682	Alpha-2B adrenergic receptor	P19328	Adra2b	Rattus norvegicus (Rat)	453
328676	Alpha-2C adrenergic receptor	P18825	ADRA2C	Homo sapiens (Human)	462
328667	D(1A) dopamine receptor	P21728	DRD1	Homo sapiens (Human)	446
328669	D(1A) dopamine receptor	P18901	Drd1	Rattus norvegicus (Rat)	446
328677	D(1B) dopamine receptor	P21918	DRD5	Homo sapiens (Human)	477
328680	D(1B) dopamine receptor	P25115	Drd5	Rattus norvegicus (Rat)	475
328670	D(2) dopamine receptor	P61169	Drd2	Rattus norvegicus (Rat)	444
328674	D(2) dopamine receptor	P20288	DRD2	Bos taurus (Bovine)	444
328681	D(2) dopamine receptor	P14416	DRD2	Homo sapiens (Human)	443
554906	D(4) dopamine receptor	P21917	DRD4	Homo sapiens (Human)	467
328675	Trace amine-associated receptor 1	Q96RJ0	TAAR1	Homo sapiens (Human)	339

zhanglabzhanggroup.org | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218