Home Research Services Publications People Teaching Job Opening Facilities News Forum Lab Only
Online Services

I-TASSER QUARK LOMETS COACH COFACTOR MetaGO MUSTER SEGMER FG-MD ModRefiner REMO DEMO SPRING COTH BSpred SVMSEQ ANGLOR BSP-SLIM SAXSTER ThreaDom ThreaDomEx EvoDesign GPCR-I-TASSER BindProf BindProfX ResQ IonCom STRUM DAMpred

TM-score TM-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR NeBcon WDL-RF ATPbind DockRMSD

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP TM-fold DECOYS POTENTIAL RW/RWplus HPSF THE-DB CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13

You can:

Ligand

NameTAMSULOSIN
Molecular formulaC20H28N2O5S
IUPAC name5-[(2R)-2-[2-(2-ethoxyphenoxy)ethylamino]propyl]-2-methoxybenzenesulfonamide
Molecular weight408.513
Hydrogen bond acceptor7
Hydrogen bond donor2
XlogP2.7
Synonyms106133-20-4
Tamsulosina
Tamsulosine
Tamsulosinum
(R)-5-(2-((2-(2-Ethoxyphenoxy)ethyl)amino)propyl)-2-methoxybenzenesulfonamide
[ Show all ]
Inchi KeyDRHKJLXJIQTDTD-OAHLLOKOSA-N
Inchi IDInChI=1S/C20H28N2O5S/c1-4-26-17-7-5-6-8-18(17)27-12-11-22-15(2)13-16-9-10-19(25-3)20(14-16)28(21,23)24/h5-10,14-15,22H,4,11-13H2,1-3H3,(H2,21,23,24)/t15-/m1/s1
PubChem CID129211
ChEMBLCHEMBL836
IUPHAR488
BindingDB50060964
DrugBankDB00706

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Total entries: 19
Page:  / 1 

GLASS IDNameUniProtGeneSpeciesLength
669555-hydroxytryptamine receptor 1AP08908HTR1AHomo sapiens (Human)422
669645-hydroxytryptamine receptor 7P34969HTR7Homo sapiens (Human)479
66954Alpha-1A adrenergic receptorP35348ADRA1AHomo sapiens (Human)466
66962Alpha-1A adrenergic receptorP18130ADRA1ABos taurus (Bovine)466
66963Alpha-1A adrenergic receptorO02824ADRA1AOryctolagus cuniculus (Rabbit)466
66965Alpha-1A adrenergic receptorP43140Adra1aRattus norvegicus (Rat)466
66953Alpha-1B adrenergic receptorP35368ADRA1BHomo sapiens (Human)520
66959Alpha-1B adrenergic receptorP15823Adra1bRattus norvegicus (Rat)515
66968Alpha-1B adrenergic receptorP18841ADRA1BMesocricetus auratus (Golden hamster)515
66956Alpha-1D adrenergic receptorP23944Adra1dRattus norvegicus (Rat)561
66957Alpha-1D adrenergic receptorP25100ADRA1DHomo sapiens (Human)572
66950Alpha-2A adrenergic receptorP08913ADRA2AHomo sapiens (Human)450
66960Alpha-2B adrenergic receptorP18089ADRA2BHomo sapiens (Human)450
66966Alpha-2B adrenergic receptorP19328Adra2bRattus norvegicus (Rat)453
66952Alpha-2C adrenergic receptorP18825ADRA2CHomo sapiens (Human)462
66958D(2) dopamine receptorP14416DRD2Homo sapiens (Human)443
66951D(3) dopamine receptorP35462DRD3Homo sapiens (Human)400
66967D(4) dopamine receptorP21917DRD4Homo sapiens (Human)467
66961Histamine H1 receptorP31389HRH1Cavia porcellus (Guinea pig)488

yangzhanglabumich.edu | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218