You can:
Name | Alpha-1A adrenergic receptor |
---|---|
Species | Bos taurus (Bovine) |
Gene | ADRA1A |
Synonym | Alpha-1A adrenoceptor Alpha-1A adrenoreceptor Alpha-1C adrenergic receptor |
Disease | N/A for non-human GPCRs |
Length | 466 |
Amino acid sequence | MVFLSGNASDSSNCTHPPPPVNISKAILLGVILGGLILFGVLGNILVILSVACHRHLHSVTHYYIVNLAVADLLLTSTVLPFSAIFEILGYWAFGRVFCNVWAAVDVLCCTASIMGLCIISIDRYIGVSYPLRYPTIVTQKRGLMALLCVWALSLVISIGPLFGWRQPAPEDETICQINEEPGYVLFSALGSFYVPLTIILVMYCRVYVVAKRESRGLKSGLKTDKSDSEQVTLRIHRKNAQVGGSGVTSAKNKTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFFPDFRPSETVFKIAFWLGYLNSCINPIIYPCSSQEFKKAFQNVLRIQCLRRKQSSKHTLGYTLHAPSHVLEGQHKDLVRIPVGSAETFYKISKTDGVCEWKIFSSLPRGSARMAVARDPSACTTARVRSKSFLQVCCCLGPSTPSHGENHQIPTIKIHTISLSENGEEV |
UniProt | P18130 |
Protein Data Bank | N/A |
GPCR-HGmod model | N/A |
3D structure model | No available structures or models |
BioLiP | N/A |
Therapeutic Target Database | N/A |
ChEMBL | CHEMBL4892 |
IUPHAR | N/A |
DrugBank | N/A |
You can:
GLASS ID | Molecule | Formula | Molecular weight | H-bond acceptor / donor | XlogP | Lipinski's druglikeness |
---|---|---|---|---|---|---|
1635 | CHEMBL1259079 | C26H28N2S | 400.584 | 3 / 0 | 5.7 | No |
4219 | CHEMBL25984 | C15H23NO | 233.355 | 2 / 0 | 3.8 | Yes |
4975 | CHEMBL50188 | C25H36N2O4 | 428.573 | 5 / 0 | 4.2 | Yes |
5548 | CHEMBL50722 | C25H36N2O5 | 444.572 | 6 / 0 | 4.3 | Yes |
5560 | CHEMBL18270 | C11H14N2 | 174.247 | 2 / 0 | 1.1 | Yes |
5920 | CHEMBL50722 | C27H38N2O9 | 534.606 | 10 / 2 | N/A | No |
6839 | CHEMBL1259231 | C23H26N4S | 390.549 | 4 / 0 | 3.7 | Yes |
8118 | CHEMBL317333 | C26H24FN5 | 425.511 | 5 / 0 | 4.0 | Yes |
8313 | CHEMBL1259080 | C27H30N2S | 414.611 | 3 / 0 | 6.1 | No |
10049 | Abanoquil | C22H25N3O4 | 395.459 | 7 / 1 | 3.4 | Yes |
11806 | CHEMBL54266 | C23H32N2O4S | 432.579 | 6 / 1 | 4.3 | Yes |
13649 | 8-OH-Dpat | C16H25NO | 247.382 | 2 / 1 | 4.1 | Yes |
17894 | Bmy-7378 | C22H31N3O3 | 385.508 | 5 / 0 | 2.8 | Yes |
19609 | CHEMBL327116 | C15H19N3O2S | 305.396 | 4 / 2 | 2.1 | Yes |
21598 | CHEMBL14213 | C26H28N4O3S | 476.595 | 6 / 0 | 4.1 | Yes |
21693 | CHEMBL89916 | C26H39N5O2 | 453.631 | 6 / 1 | 4.4 | Yes |
26561 | Rauwolscine | C21H26N2O3 | 354.45 | 4 / 2 | 2.9 | Yes |
26588 | Yohimbine | C21H26N2O3 | 354.45 | 4 / 2 | 2.9 | Yes |
28844 | 1-(3,5-dichloropyridin-2-yl)piperazine | C9H11Cl2N3 | 232.108 | 3 / 1 | 1.9 | Yes |
32864 | CHEMBL1203301 | C22H26N4O5S | 458.533 | 9 / 2 | 1.8 | Yes |
33287 | CHEMBL176365 | C20H21N3 | 303.409 | 2 / 0 | 2.2 | Yes |
33854 | CHEMBL2325928 | C24H25FN4 | 388.49 | 3 / 0 | 4.3 | Yes |
37838 | CHEMBL327527 | C27H30FN7O | 487.583 | 5 / 1 | 3.2 | Yes |
39214 | CHEMBL92901 | C22H31N5O2 | 397.523 | 6 / 2 | 3.3 | Yes |
41315 | CHEMBL60318 | C20H22FN3OS | 371.474 | 5 / 0 | 3.9 | Yes |
44149 | CHEMBL1259158 | C25H33N3OS | 423.619 | 4 / 1 | 4.2 | Yes |
537249 | DEXMEDETOMIDINE | C13H16N2 | 200.285 | 1 / 1 | 3.1 | Yes |
54610 | CHEMBL48925 | C25H34N2O4 | 426.557 | 5 / 1 | 4.6 | Yes |
56700 | cisapride | C23H29ClFN3O4 | 465.95 | 7 / 2 | 3.4 | Yes |
57188 | CID 44350012 | C17H25N5O4 | 363.418 | 7 / 3 | N/A | N/A |
57406 | CHEMBL298534 | C24H31FN2O3 | 414.521 | 5 / 1 | 4.7 | Yes |
59262 | CHEMBL64167 | C20H23N3OS | 353.484 | 4 / 0 | 3.8 | Yes |
62213 | spiperone | C23H26FN3O2 | 395.478 | 5 / 1 | 3.0 | Yes |
62316 | CHEMBL51888 | C22H30N2O4S | 418.552 | 6 / 1 | 3.9 | Yes |
62512 | CHEMBL52438 | C19H25NO | 283.415 | 2 / 0 | 5.1 | No |
63083 | CHEMBL11592 | C26H38N2O4 | 442.6 | 5 / 0 | 4.6 | Yes |
64414 | CHEMBL24619 | C30H34N4O6 | 546.624 | 10 / 1 | 5.0 | No |
66962 | TAMSULOSIN | C20H28N2O5S | 408.513 | 7 / 2 | 2.7 | Yes |
68345 | CHEMBL1203301 | C22H27ClN4O5S | 494.991 | 9 / 3 | N/A | N/A |
68942 | CHEMBL301060 | C28H40N2O8 | 532.634 | 9 / 2 | N/A | No |
69395 | CHEMBL328187 | C27H30FN7O | 487.583 | 5 / 1 | 2.9 | Yes |
69950 | CHEMBL93923 | C28H31FN6O | 486.595 | 4 / 1 | 3.4 | Yes |
71132 | CHEMBL47471 | C16H18ClN3 | 287.791 | 3 / 0 | 3.2 | Yes |
71937 | CHEMBL17926 | C11H13ClN2 | 208.689 | 2 / 0 | 1.7 | Yes |
72743 | CHEMBL59741 | C20H20F3N3OS | 407.455 | 7 / 1 | 4.5 | Yes |
76589 | (R)-zacopride | C15H20ClN3O2 | 309.794 | 4 / 2 | 1.7 | Yes |
77261 | SDZ-205557 | C14H21ClN2O3 | 300.783 | 5 / 1 | 3.2 | Yes |
77709 | CHEMBL91876 | C24H33N5O2 | 423.561 | 6 / 1 | 3.6 | Yes |
77776 | CHEMBL1259188 | C27H31FN8O | 502.598 | 6 / 1 | 3.6 | No |
79462 | CHEMBL156283 | C10H15N3 | 177.251 | 2 / 1 | 1.0 | Yes |
79510 | CHEMBL368475 | C20H21F3N2S | 378.457 | 5 / 0 | 4.2 | Yes |
82722 | 87394-57-8 | C10H14ClN3 | 211.693 | 3 / 0 | 1.7 | Yes |
85376 | 87394-63-6 | C10H12F3N3 | 231.222 | 6 / 1 | 1.5 | Yes |
87885 | CHEMBL1259062 | C26H28N2S | 400.584 | 3 / 0 | 5.7 | No |
88013 | CHEMBL420997 | C25H25FN6 | 428.515 | 5 / 0 | 3.8 | Yes |
88084 | CHEMBL296395 | C22H24N2O4 | 380.444 | 5 / 1 | 2.9 | Yes |
88219 | CHEMBL1259042 | C23H24N4S | 388.533 | 5 / 0 | 3.6 | Yes |
88270 | CHEMBL50993 | C25H36N2O3 | 412.574 | 4 / 0 | 4.6 | Yes |
92983 | CHEMBL300735 | C24H34N2O4S | 446.606 | 6 / 1 | 4.6 | Yes |
94253 | CHEMBL330060 | C23H32N4O2 | 396.535 | 5 / 1 | 3.9 | Yes |
95815 | CHEMBL338704 | C11H14BrN5 | 296.172 | 4 / 0 | 2.0 | Yes |
95876 | CHEMBL538537 | C12H18ClN5 | 267.761 | 4 / 2 | N/A | N/A |
538411 | clonidine | C9H9Cl2N3 | 230.092 | 1 / 2 | 1.6 | Yes |
99329 | CHEMBL368413 | C19H22N2 | 278.399 | 1 / 0 | 2.5 | Yes |
101634 | 5-Meo-dpac | C16H25NO2 | 263.381 | 3 / 0 | 3.8 | Yes |
102088 | CHEMBL91093 | C26H39N5O2 | 453.631 | 6 / 1 | 4.9 | Yes |
108400 | CHEMBL299007 | C10H14ClN3 | 211.693 | 3 / 1 | 1.6 | Yes |
108595 | WB-4101 | C19H23NO5 | 345.395 | 6 / 1 | 2.9 | Yes |
109132 | SERTINDOLE | C24H26ClFN4O | 440.947 | 3 / 1 | 4.1 | Yes |
109375 | 1-(2-Pyridyl)piperazine | C9H13N3 | 163.224 | 3 / 1 | 0.7 | Yes |
112354 | CHEMBL285010 | C14H19NO2 | 233.311 | 3 / 0 | 2.5 | Yes |
113068 | CHEMBL13735 | C19H22N4O3S | 386.47 | 6 / 1 | 2.2 | Yes |
115730 | 5-Methylurapidil | C21H31N5O3 | 401.511 | 6 / 1 | 1.9 | Yes |
117770 | 1-(3-chloropyridin-2-yl)piperazine | C9H12ClN3 | 197.666 | 3 / 1 | 1.3 | Yes |
118312 | A-119637 | C25H26N4O3S | 462.568 | 6 / 1 | 3.9 | Yes |
120662 | CHEMBL54089 | C26H30N2O8 | 498.532 | 9 / 2 | N/A | N/A |
120831 | IDAZOXAN | C11H12N2O2 | 204.229 | 3 / 1 | 0.7 | Yes |
121140 | 1-(3-fluoropyridin-2-yl)piperazine | C9H12FN3 | 181.214 | 4 / 1 | 0.8 | Yes |
121544 | CHEMBL88512 | C20H27N5O2 | 369.469 | 6 / 2 | 2.6 | Yes |
121672 | CHEMBL294730 | C22H27N3O2S | 397.537 | 5 / 0 | 4.1 | Yes |
122583 | 1-(3-nitropyridin-2-yl)piperazine | C9H12N4O2 | 208.221 | 5 / 1 | 0.5 | Yes |
125278 | CHEMBL178376 | C20H19N3 | 301.393 | 2 / 0 | 2.5 | Yes |
131342 | prazosin | C19H21N5O4 | 383.408 | 8 / 1 | 2.0 | Yes |
561433 | CHEMBL307364 | C10H11N5O | 217.232 | 3 / 4 | 0.3 | Yes |
133950 | CHEMBL346492 | C15H17NS | 243.368 | 2 / 0 | 3.7 | Yes |
136069 | CHEMBL59823 | C24H31N3O3 | 409.53 | 5 / 0 | 3.6 | Yes |
140507 | CHEMBL2325931 | C24H24N4 | 368.484 | 3 / 0 | 3.7 | Yes |
140733 | CHEMBL52396 | C25H30N2O4 | 422.525 | 5 / 0 | 4.3 | Yes |
142028 | CHEMBL88820 | C23H30N4O3 | 410.518 | 5 / 1 | 2.6 | Yes |
142053 | CHEMBL61819 | C23H29N3O2S | 411.564 | 5 / 0 | 4.4 | Yes |
142919 | 1',2',3',6'-Tetrahydro-[2,4']bipyridinyl | C10H12N2 | 160.22 | 2 / 1 | 0.6 | Yes |
143013 | CHEMBL17605 | C11H14N2 | 174.247 | 2 / 0 | 1.1 | Yes |
143147 | CHEMBL545198 | C23H26N2O4 | 394.471 | 5 / 0 | 3.6 | Yes |
147182 | CHEMBL92109 | C23H33N5O | 395.551 | 5 / 1 | 3.9 | Yes |
148418 | CHEMBL346016 | C11H15NS | 193.308 | 2 / 0 | 2.4 | Yes |
150288 | CHEMBL366388 | C24H29FN2O | 380.507 | 4 / 0 | 4.1 | Yes |
152921 | CHEMBL51985 | C27H41N2O4+ | 457.635 | 4 / 0 | 4.6 | Yes |
153120 | CHEMBL545198 | C23H27ClN2O4 | 430.929 | 5 / 1 | N/A | N/A |
153541 | CHEMBL1259005 | C24H26N2S2 | 406.606 | 4 / 0 | 5.4 | No |
159380 | CHEMBL1259113 | C20H25N3S | 339.501 | 4 / 1 | 2.6 | Yes |
zhanglabzhanggroup.org | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218