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Ligand

Namethiothixene
Molecular formulaC23H29N3O2S2
IUPAC name(9Z)-N,N-dimethyl-9-[3-(4-methylpiperazin-1-yl)propylidene]thioxanthene-2-sulfonamide
Molecular weight443.624
Hydrogen bond acceptor6
Hydrogen bond donor0
XlogP3.8
Synonymscis-Thiothixene
Tiotixene
Navane
(Z)-Thiothixene
Thiothixine
[ Show all ]
Inchi KeyGFBKORZTTCHDGY-UWVJOHFNSA-N
Inchi IDInChI=1S/C23H29N3O2S2/c1-24(2)30(27,28)18-10-11-23-21(17-18)19(20-7-4-5-9-22(20)29-23)8-6-12-26-15-13-25(3)14-16-26/h4-5,7-11,17H,6,12-16H2,1-3H3/b19-8-
PubChem CID941651
ChEMBLCHEMBL1201
IUPHAR212
BindingDB78576
DrugBankDB01623

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

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Total entries: 28
Page:  / 2 

GLASS IDNameUniProtGeneSpeciesLength
949005-hydroxytryptamine receptor 2AP28223HTR2AHomo sapiens (Human)471
5558245-hydroxytryptamine receptor 2AP14842Htr2aRattus norvegicus (Rat)471
949135-hydroxytryptamine receptor 2CP28335HTR2CHomo sapiens (Human)458
949155-hydroxytryptamine receptor 2CP08909Htr2cRattus norvegicus (Rat)460
949055-hydroxytryptamine receptor 6P31388Htr6Rattus norvegicus (Rat)436
949125-hydroxytryptamine receptor 6P50406HTR6Homo sapiens (Human)440
5558235-hydroxytryptamine receptor 7P32305Htr7Rattus norvegicus (Rat)448
94917Alpha-1A adrenergic receptorP43140Adra1aRattus norvegicus (Rat)466
555820Alpha-1A adrenergic receptorP35348ADRA1AHomo sapiens (Human)466
94908Alpha-2A adrenergic receptorP08913ADRA2AHomo sapiens (Human)450
94903Alpha-2C adrenergic receptorP22086Adra2cRattus norvegicus (Rat)458
460064Beta-2 adrenergic receptorP07550ADRB2Homo sapiens (Human)413
94904D(1A) dopamine receptorQ95136DRD1Bos taurus (Bovine)446
94906D(1A) dopamine receptorP21728DRD1Homo sapiens (Human)446
94911D(1A) dopamine receptorP18901Drd1Rattus norvegicus (Rat)446
94909D(2) dopamine receptorP14416DRD2Homo sapiens (Human)443
555819D(2) dopamine receptorP20288DRD2Bos taurus (Bovine)444
555822D(2) dopamine receptorP61169Drd2Rattus norvegicus (Rat)444
94899D(4) dopamine receptorP30729Drd4Rattus norvegicus (Rat)387
555821D(4) dopamine receptorP21917DRD4Homo sapiens (Human)467

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