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BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP TM-fold DECOYS POTENTIAL RW/RWplus HPSF THE-DB CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13

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GPCR

NameD(1A) dopamine receptor
SpeciesBos taurus (Bovine)
GeneDRD1
SynonymDopamine D1 receptor
DiseaseN/A for non-human GPCRs
Length446
Amino acid sequenceMRTLNTSTMEGTGLVAERDFSFRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNFFVISLAVSDLLVAVLVMPWKAVAEIAGFWPFGSFCNIWVAFDIMCSTASILNLCVISVDRYWAISSPFRYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTGPSEGNATSLGKTINNCDSSLSRTYAISSSLISFYIPVAIMIVTYTRIYRIAQKQIRRISALERAAVHAKNCQTTTGNGNPMECSQPESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFILNCMVPFCGSGETKPFCIDSITFDVFVWFGWANSSLNPIIYAFNADFRKAFSTLLGCYRLCPTTNNAIETVSINNNGAVVFSSHHEPRGSISKDCNVVYLIPHAVGSSEGLKKEEAVGIAKPLEKLSPALSVILDYDTDVSLEKIQPITQNGQHPT
UniProtQ95136
Protein Data BankN/A
GPCR-HGmod modelN/A
3D structure modelNo available structures or models
BioLiPN/A
Therapeutic Target DatabaseN/A
ChEMBLCHEMBL2967
IUPHARN/A
DrugBankN/A

Known ligands

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Total entries: 399
Page:  / 4 

GLASS IDMoleculeFormulaMolecular weightH-bond acceptor / donorXlogPLipinski's druglikeness
21002D structureCHEMBL558838C21H28N6O380.4966 / 12.9Yes
42232D structureCHEMBL25984C15H23NO233.3552 / 03.8Yes
46862D structureMoperoneC22H26FNO2355.4534 / 13.0Yes
49722D structureCHEMBL50188C25H36N2O4428.5735 / 04.2Yes
55472D structureCHEMBL50722C25H36N2O5444.5726 / 04.3Yes
59152D structureCHEMBL50722C27H38N2O9534.60610 / 2N/ANo
91462D structureCHEMBL144114C16H25N231.3831 / 04.1Yes
105292D structureCHEMBL341825C16H25N231.3831 / 04.1Yes
111952D structureCHEMBL2113718C16H18N4266.3483 / 12.2Yes
117232D structurepropranololC16H21NO2259.3493 / 23.0Yes
117702D structureCHEMBL554692C20H24ClN5369.8974 / 04.4Yes
118112D structureCHEMBL54266C23H32N2O4S432.5796 / 14.3Yes
131302D structureCHEMBL107529C19H21N3O307.3973 / 02.7Yes
136192D structureADTNC10H13NO2179.2193 / 31.4Yes
136792D structure8-OH-DpatC16H25NO247.3822 / 14.1Yes
167922D structurePipamperoneC21H30FN3O2375.4885 / 12.0Yes
177692D structureCHEMBL160396C19H21ClN4O356.8544 / 12.2Yes
179292D structureCHEMBL492042C19H20BrClN4419.7513 / 14.7Yes
201972D structureimipramineC19H24N2280.4152 / 04.8Yes
206172D structureCHEMBL318924C14H24N2220.361 / 02.9Yes
233392D structureLevosulpirideC15H23N3O4S341.4266 / 20.6Yes
233642D structuresulpirideC15H23N3O4S341.4266 / 20.6Yes
250872D structureCHEMBL544711C14H21N203.3291 / 03.4Yes
255132D structureTeflutixolC23H26F4N2OS454.5288 / 14.6Yes
255272D structureUNII-NGJ1K8EOK1C21H26N4334.4673 / 12.9Yes
255312D structureCHEMBL352925C21H26N4334.4673 / 12.9Yes
267722D structureCHEMBL328925C19H21ClN4O356.8544 / 12.2Yes
299892D structureCHEMBL561123C22H28N6O2408.5065 / 11.1Yes
330322D structureCHEMBL104201C20H20N4316.4083 / 02.7Yes
339532D structureCleboprideC20H24ClN3O2373.8814 / 23.2Yes
389722D structureUNII-F52O5YF6CAC24H25F4NOS451.5247 / 15.9No
389742D structurecis-PiflutixolC24H25F4NOS451.5247 / 15.9No
405162D structureCHEMBL165022C17H25N243.3941 / 04.2Yes
410592D structureCHEMBL267853C17H18ClN5327.8164 / 03.2Yes
429022D structureCHEMBL559868C18H19ClN4326.8283 / 13.4Yes
437902D structureCHEMBL483864C19H21ClN4340.8553 / 14.0Yes
458982D structureCHEMBL325818C24H25BrN2O2453.383 / 15.0Yes
460162D structureCHEMBL325104C18H20N2264.3721 / 02.9Yes
508742D structureCHEMBL520019C17H19ClN6342.8315 / 12.6Yes
553582D structureCHEMBL109472C31H28N2O2460.5773 / 16.2No
562542D structureCHEMBL294394C15H19N3241.3382 / 12.2Yes
564192D structureCHEMBL326454C21H26ClN3O2387.9084 / 23.9Yes
564232D structureCHEMBL111749C21H26ClN3O2387.9084 / 23.9Yes
566942D structurecisaprideC23H29ClFN3O4465.957 / 23.4Yes
569572D structureCHEMBL544961C15H29N223.4041 / 04.9Yes
574082D structureCHEMBL298534C24H31FN2O3414.5215 / 14.7Yes
622402D structurespiperoneC23H26FN3O2395.4785 / 13.0Yes
623192D structureCHEMBL51888C22H30N2O4S418.5526 / 13.9Yes
625072D structureCHEMBL52438C19H25NO283.4152 / 05.1No
627022D structureCHEMBL168571C21H24N4O348.454 / 12.3Yes
627042D structureCHEMBL168541C21H24N4O348.454 / 12.3Yes
630822D structureCHEMBL11592C26H38N2O4442.65 / 04.6Yes
641892D structureCHEMBL550392C20H25N5335.4554 / 03.8Yes
646712D structurePD-168077C20H22N4O334.4234 / 13.0Yes
647632D structureCHEMBL338119C16H23N3O2289.3793 / 22.5Yes
655882D structureCHEMBL510055C20H23ClN4O370.8814 / 14.0Yes
663372D structureCHEMBL483247C19H20Cl2N4375.2973 / 14.6Yes
666412D structureCHEMBL131186C18H29N3O2319.4493 / 22.4Yes
672262D structureCHEMBL62601C27H28BrN3O2506.4445 / 15.2No
678422D structureCHEMBL553258C15H23N217.3561 / 03.8Yes
686232D structureFAUC 213C18H19ClN4326.8283 / 03.2Yes
689312D structureCHEMBL268558C22H21ClN4376.8883 / 04.4Yes
689462D structureCHEMBL301060C28H40N2O8532.6349 / 2N/ANo
701622D structureCHEMBL165171C29H33N395.591 / 07.8No
718662D structure1-(1-Benzylpiperidin-4-yl)-1H-pyrrole-2-carbaldehydeC17H20N2O268.362 / 02.4Yes
737522D structurepramipexoleC10H17N3S211.3274 / 21.9Yes
737732D structurech56C19H19N5317.3964 / 12.2Yes
754422D structureCHEMBL550920C20H25N5O351.4545 / 03.3Yes
758082D structureCHEMBL131120C14H22N4246.3583 / 13.1Yes
760912D structureBENPERIDOLC22H24FN3O2381.4514 / 13.7Yes
765812D structure(R)-zacoprideC15H20ClN3O2309.7944 / 21.7Yes
775552D structureCHEMBL99291C15H26N2O250.3862 / 12.1Yes
775592D structureCHEMBL95230C15H26N2O250.3862 / 12.1Yes
779232D structureCHEMBL177031C23H28ClN3O397.9473 / 14.0Yes
781152D structureCHEMBL164950C15H23N3245.373 / 02.9Yes
781882D structuredomperidoneC22H24ClN5O2425.9173 / 23.9Yes
823302D structureCHEMBL293956C19H19N5317.3964 / 12.3Yes
824562D structureCHEMBL485499C19H21BrN4385.3093 / 14.1Yes
838782D structureKetanserinC22H22FN3O3395.4345 / 12.6Yes
840142D structureCHEMBL424575C24H32ClN3O2429.9894 / 25.0Yes
840182D structureCHEMBL168274C24H32ClN3O2429.9894 / 25.0Yes
840202D structureCHEMBL168611C24H32ClN3O2429.9894 / 25.0Yes
840272D structureCHEMBL168544C24H32ClN3O2429.9894 / 25.0Yes
870332D structure(A+/-)-Quinpirole dihydrochlorideC13H21N3219.3322 / 12.3Yes
870772D structureQUINPIROLEC13H21N3219.3322 / 12.3Yes
878562D structureCHEMBL353087C22H26ClN3O3415.9184 / 22.9Yes
878632D structureCHEMBL167032C22H26ClN3O3415.9184 / 22.9Yes
880802D structureCHEMBL296395C22H24N2O4380.4445 / 12.9Yes
882692D structureCHEMBL50993C25H36N2O3412.5744 / 04.6Yes
884082D structureCHEMBL156369C19H21ClN4340.8553 / 03.5Yes
900832D structureCHEMBL2092872C16H26ClN267.8411 / 1N/AN/A
900852D structureCHEMBL1788303C16H26ClN267.8411 / 1N/AN/A
900882D structure3-(3,4-Dimethylphenyl)-1-propyl-piperidine hydrochlorideC16H26ClN267.8411 / 1N/AN/A
905072D structureCHEMBL64139C23H26BrN3OS472.4455 / 14.6Yes
905092D structureCHEMBL2111528C23H26BrN3OS472.4455 / 14.6Yes
929892D structureCHEMBL300735C24H34N2O4S446.6066 / 14.6Yes
945112D structureD-Lysergic acid amideC16H18N3O+268.341 / 31.6Yes
949042D structurethiothixeneC23H29N3O2S2443.6246 / 03.8Yes
952322D structureCHEMBL354210C23H29N3O363.5053 / 13.3Yes
972442D structureCogentinolC21H25NO307.4372 / 04.5Yes

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